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The Latest Breaking News from 49ers

‘Madden’ simulation predicted Cardinals upset of 49ers

Kyler Murray threw three TD passes, two to Greg Dortch in a 37-27 upset win in a Madden simulation of the Week 5 game.

USA Today Sports Media Group

NFL picks: Cards Wire staff predicts Cardinals-49ers outcome

USA Today Sports Media Group

Trey McBride, George Kittle injury update, availability in Week 5 Cardinals vs. 49ers

ESPN's Adam Schefter gives an update about whether or not Trey McBride and George Kittle will play in Week 5.

USA Today Sports Media Group

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49ers Get Encouraging Update on Complicated Christian McCaffrey Injury

McCaffrey has not yet made his 2024 debut for the Niners.

Sports Illustrated

Cardinals vs. 49ers: The heat is on in Santa Clara Sunday

The unseasonably high temperatures could affect the Cardinals and 49ers in their game on Sunday.

USA Today Sports Media Group

History lesson reveals what makes 49ers’ ground game a consistent success

49ers head coach Kyle Shanahan saw his father find great success with a variety of running backs.

USA Today Sports Media Group

49ers activate one DL off IR, place another DL on IR

49ers roster moves ahead of Week 5:

USA Today Sports Media Group

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Cardinals’ practice squad elevations for Week 5 make it look like a starter is out

Check out the two players the Cardinals elevated to the active roster for their game against the 49ers and what the moves mean.

USA Today Sports Media Group

Trey McBride’s availability in question with rib injury

The Cardinals downgraded him from having no injury designation to being questionable with an injury to his ribs.

USA Today Sports Media Group

49ers prepare for big free agent losses in mock draft

The Notre Dame defensive back was named to the 2024 AP All-American second team.

USA Today Sports Media Group

Cardinals-49ers preview, predictions, picks and best bets

Jess Root and Seth Cox break down the game in Week 5 and make predictions.

USA Today Sports Media Group

NFL picks: ‘H-Bomb’ underdogs continue their hot streak

A look at the performance of big underdogs this season and who are the big underdogs in Week 5.

USA Today Sports Media Group

NFL Denies 49ers' Plea to Switch to White Uniforms Amid Record Santa Clara Heat

San Francisco is scheduled to play in scorching conditions Sunday.

Sports Illustrated

49ers Week 5 injury report: George Kittle, Fred Warner questionable

Lots going on with the 49ers' Week 5 injury report:

USA Today Sports Media Group

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Will Trey McBride’s return help jump start Cardinals’ offense?

The Cardinals missed McBride in their Week 4 loss.

USA Today Sports Media Group

Cardinals TE Trey McBride out of concussion protocol, will play Sunday vs. 49ers

The Cardinals will have Trey McBride back in the lineup on Sunday against the 49ers.

USA Today Sports Media Group

2 injured 49ers stars return to practice ahead of Week 5

Fred Warner and George Kittle practiced on Friday.

USA Today Sports Media Group

NFL Week 5 picks: Experts heavily favoring Packers over Rams

There's little doubt which team NFL experts like in Sunday's Rams-Packers matchup at SoFi Stadium

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USA Today Sports Media Group

PFF metric shows how bad the Patriots’ passing offense has been

Things can't get much worse than this, right?

USA Today Sports Media Group

49ers out-of-nowhere superstar has chance to set franchise record

Jordan Mason is on track to break a 49ers record.

USA Today Sports Media Group

How 49ers are preparing for potentially missing Fred Warner in Week 5

Fred Warner has missed the first two days of practice this week..

USA Today Sports Media Group

49ers lead NFL in crucial offensive category by a lot over last 3 years

The 49ers create so many explosive plays it's ridiculous.

USA Today Sports Media Group

Indianapolis Colts CB Sam Womack performs well in much larger role

Indianapolis Colts cornerback Sam Womack took on his largest workload this past week and had his best performance.

USA Today Sports Media Group

49ers get bad injury news with key NFC West matchup approaching

The Niners practice report on Thursday is ugly.

USA Today Sports Media Group

49ers will need an answer for Cardinals WR Marvin Harrison Jr.

The Arizona Cardinals should feel comfortable challenging the 49ers in 1-on-1 situations with WR Marvin Harrison Jr.

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