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The Latest Breaking News from 49ers

49ers rookie RB Isaac Guerendo finds end zone vs. Bills

During Sunday Night Football against the Bills, Isaac Guerendo punched in his second touchdown of his rookie campaign.

USA Today Sports Media Group

Cris Collinsworth Had the Perfect Metaphor For 49ers’ Costly Fumble vs. Bills

What a wild moment at Highmark Stadium.

Sports Illustrated

Josh Allen threw a touchdown pass to himself on ridiculous Bills’ lateral play

Yes, really!

USA Today Sports Media Group

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Patrick Mahomes Had Three-Word Reaction to Josh Allen’s Ridiculous TD vs. 49ers

This may have been the play of the year.

Sports Illustrated

Bills, Josh Allen Pull Off Incredible Lateral Touchdown in Snow vs. 49ers

That was wild.

Sports Illustrated

Bills Fan Hilariously Tries to Knock Down 49ers’ FG Attempt by Throwing Snowball

This was so close.

Sports Illustrated

Christian McCaffrey ruled out of 49ers’ game vs Bills

San Francisco running back Christian McCaffrey was officially ruled out of the 49ers' Sunday Night Football contest at the Buffalo Bills.

USA Today Sports Media Group

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NFL World Reacts to 49ers' Christian McCaffrey's Apparent Knee Injury vs. Bills

A brutal blow to one of the league's best.

Sports Illustrated

Fred Warner returns vs Bills despite cramps

San Francisco 49ers linebacker Fred Warner exited with cramps, but then later returned in the first half vs. the Buffalo Bills.

USA Today Sports Media Group

Christian McCaffrey leaves 49ers game vs Bills with knee injury

San Francisco star running back Christian McCaffrey exited the 49ers Sunday Night Football game against the Bills with a knee injury.

USA Today Sports Media Group

49ers injury update: DL Kevin Givens (chest) questionable to return vs. Bills

The 49ers defensive line depth will continue to be tested on Sunday Night Football against the Bills.

USA Today Sports Media Group

49ers injury news: QB Brock Purdy officially active vs. Bills

Brock Purdy is officially back.

USA Today Sports Media Group

Video of Buffalo weather for 49ers showdown with Bills is insane

The weather in Buffalo is nuts.

USA Today Sports Media Group

Bills wide receiver Mack Hollins really showed up barefoot for the snow game against the 49ers

Even in the snow?!

USA Today Sports Media Group

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USA Today Sports Media Group

Wild video of Buffalo blizzard shows how snowy the Bills stadium is ahead of 49ers game

It's VERY snowy in Buffalo.

USA Today Sports Media Group

49ers can play spoiler for Bills playoff chances

The San Francisco 49ers have slim playoff hopes of their own, but they can also play spoiler against the Buffalo Bills in Week 13.

USA Today Sports Media Group

Will Brock Purdy play this week? Injury updates for 49ers QB

49ers QB Brock Purdy is dealing with a shoulder injury. Here are the latest updates.

USA Today Sports Media Group

Orchard Park, NY, engulfed in snowstorm on eve of 49ers-Bills

A massive snowstorm hit the Buffalo area

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USA Today Sports Media Group

49ers fill open roster spot with CB, elevate 2 others before Week 13

Roster moves for the 49ers:

USA Today Sports Media Group

49ers waive maligned former 7th-round WR before Week 13

Ronnie Bell is gone.

Sports Illustrated

Kyle Shanahan Gives Brock Purdy Injury Update Ahead of 49ers-Bills Clash

The 24-year-old quarterback missed last Sunday's game against the Packers with a shoulder injury.

USA Today Sports Media Group

49ers injury report full of bad news despite good Brock Purdy update

The 49ers Week 13 injury report is… not good.

USA Today Sports Media Group

49ers add familiar OL to practice squad, release former 1st-round pick

A practice squad move for the 49ers.

Sports Illustrated

Matt Eberflus Confident He Will Coach the Bears in Next Game vs. 49ers

Eberflus was pressed on his job status following clock management issues in the Bears' loss to the Lions on Thanksgiving Day.

USA Today Sports Media Group

Matt Eberflus seems confident the Bears aren’t firing him after Thanksgiving timeout debacle

Matt Eberflus already met with the front office after the disaster in Detroit

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