Sarah Palin, the Republican nominee for US vice-president in 2008, has announced her run for Alaska's only seat in the House of Representatives.
It would be Ms Palin's first run for public office since serving as John McCain's 2008 running mate, when she became the first woman to appear on a national Republican ticket.
The pair lost to Democrat Barack Obama.
"America is at a tipping point," Ms Palin said in a statement released on Twitter.
"As I've watched the far left destroy the country, I knew I had to step up and join the fight."
In her statement, Ms Palin, a staunch supporter of former president Donald Trump, appealed to conservative voters on issues of illegal immigration and "socialist" policies enacted by the Democrats.
"At this critical time in our nation's history, we need leaders who will combat the left's socialist, big-government, America-last agenda," she said.
Such fiery, anti-establishment rhetoric came to define Ms Palin's vice-presidential campaign in 2008 and served as a precursor to the rise of Mr Trump and the modern Republican Party.
She also addressed economic issues such as high inflation and petrol prices.
The 58-year-old former governor of Alaska is one of about 40 candidates.
Alaska's House seat became vacant after Republican Don Young died suddenly last month at age 88 after serving for more than four decades.
Ms Palin, a self-described "hockey mum", was one of the most-recognisable voices of the Republican Tea Party movement, and has starred in two reality television shows about her family.
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