A co-founder of women's rights group Reclaim These Streets, slammed "tone deaf" Cressida Dick, saying she hopes her departure marks an overhaul of the "rotten" at the Met Police.
Anna Birley said under Dick's watch, the Met Police was willing to "put itself above the expense of women's safety" in refusing to tackle issues of misogyny and violence against women - along with wider issues of homophobia and racism.
Commissioner Dick's resignation comes after the deaths of Sarah Everard, Sabina Nessa as well as sisters Nicole Smallman, 27, and Bibaa Henry, 46.
Sarah Everard was kidnapped, raped and killed by Met Officer Wayne Couzens, while sisters Nicole and Bibaa were killed stabbed to death in north London by Danyal Hussein.
Koci Selamaj, 36, has accepted responsibility for Sabina Nessa's death, but denies murdering the 28-year-old teenagers.
He is due to stand trial later this year.
Following a public outcry for the Met Police to do more in protecting women, Cressida Dick was slammed for saying those who feel intimidated on the street should flag down a bus or pretend to FaceTime.
Anna said: "It was absolutely tone deaf - the idea that the answer to keeping ourselves safe is to flag down a bus, phone a friend or pretend to FaceTime is quite frankly offensive.
"Her unwillingness to recognise discrimination and call it out for what it is creates toxicity.
"You can't fix something if you don't accept and recognise there's a problem."
Speaking about the need for change within the force, Anna said: "We are really pleased about this resignation. There is a rotten culture in the Met Police and one which puts itself at the expense of women's safety.
"While one person leaving doesn't fix this culture overnight, we have to hold our leadership accountable to a higher standard and we need a leader who can meet those standard.
"The past 11 months has shown this toxic culture in the Met. People of colour have always been affected by the way police treat them, but women in the last year have felt less safe.
"It was on Cressida Dick's watch that one of her officers used his position to abduct, rape and kill a woman."
Lucy went on to say the police response to calls for more support for women was "offensive".
She added: "Following this police then knocked women's doors in my neighbourhood telling them they needed to take steps to stay safe.
"Any organisation that tells women they are part of problem rather than stepping up with the right support is an issue."
Following Sarah Everard's death, Reclaim These Streets organised a vigil at Clapham Common where an inquiry later found officers used excessive force, antagonised protesters and misinterpreted coronavirus laws during their policing of the event.
Anna continued: "The way they policed the vigil showed a complete lack of understanding and highlighted these engrained issues.
"I am yet to meet a women who doesn't feel safe when she leaves the house. We hold keys in between our fingers, we share locations, wear bright clothes.
"In March we had had enough. We are tired of the burden to stay safe being placed on our shoulders when what we need is to look at who is policing us and why it's not working."