Captain Niamh Fahey opened the scoring as Liverpool secured promotion back to the top level as Championship winners.
The 101-times-capped Ireland defender swept home from a set piece to put the Reds on course for a 4-2 win over Bristol City at Ashton Gate.
Jasmine Matthews, Katie Stengel and Missy Bo Kearns were also on target for Liverpool in front of a Championship record crowd of 5,752.
Fahey’s international teammates Megan Campbell and Leanne Kiernan also started for Liverpool, and it was the former’s long throw that created the opener.
In the Premiership, Katie McCabe started for Arsenal as they ran out resounding 5-0 winners away to Leicester City.
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Megan Connolly was introduced at half time as Brighton & Hove Albion were edged out away at Manchester United, who returned to third in the league.
Ruesha Littlejohn played the whole game for Aston Villa as they dented Tottenham Hotspur’s Champions League ambitions with a 1-0 away win.
Captain Louise Quinn was one of five Irish starters, alongside Lucy Quinn, Harriet Scott, Jamie Finn and Eleanor Ryan Doyle, as Birmingham City were held to a scoreless draw by Everton.
