Eight Labour frontbenchers have resigned to back a Commons vote calling for a ceasefire in Gaza. This brings the total number of resignations since the war started to nine.
Fifty-six Labour MPs backed the Scottish National Party (SNP's) King's Speech amendment calling for "all parties to agree to an immediate ceasefire".
Overall, MPs voted 293 to 125, a majority of 168, to reject the amendment.
Labour leader Sir Keir Starmer said he regretted that party colleagues had not backed his position.
"Alongside leaders around the world, I have called throughout for adherence to international law, for humanitarian pauses to allow access for aid, food, water, utilities and medicine, and have expressed our concerns at the scale of civilian casualties," he said.
"Much more needs to be done in this regard to ease the humanitarian crisis that is unfolding in Gaza.
"And in addition to addressing the present, every leader has a duty not to go back to a failed strategy of containment and neglect, but to forge a better and more secure future for both Palestinians and Israelis.
"I regret that some colleagues felt unable to support the position tonight. But I wanted to be clear about where I stood, and where I will stand.
"Leadership is about doing the right thing. That is the least the public deserves. And the least that leadership demands."
Which Labour MPs have resigned over the Gaza ceasefire vote?
Jess Phillips, Yasmin Qureshi, Afzal Khan and Paula Barker have quit their roles.
ââMs Phillips, the most high-profile frontbencher to rebel, said it was with a "heavy heart" that she was quitting as shadow domestic violence minister.
Her resignation letter said: "This week has been one of the toughest weeks in politics since I entered Parliament.
"I have tried to do everything that I could to make it so that this was not the outcome, but it is with a heavy heart that I will be leaving my post in the shadow Home Office team.
"On this occasion, I must vote with my constituents, my head, and my heart which has felt as if it were breaking over the last four weeks with the horror of the situation in Israel and Palestine.
"I can see no route where the current military action does anything but put at risk the hope of peace and security for anyone in the region now and in the future."
Other Labour frontbenchers to have resigned are Rachel Hopkins, Sarah Owen, Naz Shah and Andy Slaughter. They faced being sacked for breaking the party whip.
In UK politics, "breaking the party whip" refers to an MP or another elected official voting against the official position or instructions of their political party. The term "whip" is derived from the idea of party discipline and control, where the party's chief whip is responsible for ensuring that members vote in line with the party's stated position on a particular issue.
Parliamentary private secretaries Dan Carden and Mary Foy were also among the 56 Labour MPs who backed the SNP amendment.
