Celtic are back in the Champions League group stage for the first time in five years and face the defending champions in their first game.
The Hoops couldn't be coming into the game in better form after destroying their Glasgow rivals Rangers 4-0 over the weekend to continue their 100% start to the season.
Both Kyogo Furuhashi and Carl Starfelt went off injured in that victory and the latter is definitely out of the Madrid game, but Furuhashi could feature.
The Spanish giants have also won all of their games to date this season, the most of recent of which came against Real Betis over the weekend.
Here's what you need to know:
Where and when is it?
The match takes place at Celtic Park on Tuesday September 6.
What time is kick-off?
The action kicks off at 8pm.
What channel is it on?
RTE Two will show the game live following the Republic of Ireland's World Cup qualifier with Slovakia. Their Champions League coverage is scheduled to start at 7.30pm.
BT Sport Sport 3 will also show live coverage of the game from 7.15pm.
Quotes corner
Celtic manager Ange Postecoglou: “I love winning games of football, I love winning trophies, I love being part of groups that do that, and every challenge I have had along the way, I have seen that as an opportunity to do that.
“It’s not like I look back on my career and see these games I have been fortunate enough to be involved in as some sort of achievement. The achievement comes after.
“It’s about making an impact, being successful, winning games of football, and that’s where you get the significance of it more.
“I am lucky that I represent a football club that’s given me a platform to be in the best club competition in the world so from that perspective I am just like the players, I want to make the most of it.”
Real Madrid boss Carlo Ancelotti: “I don’t think Celtic will change their style or attitude on the pitch. They want to play attacking football. This is absolutely normal at their home.
“We are not worried to defend because we defend well and we have defended really well in the past.
“One of the key points of the triumph last season was to defend well sometimes.
“A team has to be able to defend well and that is what we would like to do on Tuesday.
“It’s obviously going to be a difficult game. They are a lot like us – they have a good dynamic at the moment. They play with a lot of intensity but we are prepared.
“We are ready for it and hopefully we get a victory in our first game.”
Betting odds
Celtic win: 7/2
Real Madrid win: 4/6
Draw: 16/5
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