Police have arrested 21 people and seized multiple weapons as part of a crackdown after three fatal stabbings on three consecutive weekends.
GMP stepped up patrols and stop-and-search powers as they launched Operation Sycamore following the tragic deaths of three young males over just 16 days.
Kennie Carter, 16, died after being stabbed in the chest in Stretford on January 22.
A total of 13 teenagers - aged between 13 and 17 - have been arrested in connection with his death.
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All were arrested on suspicion of murder and have been bailed.
Alan Szelugowski, 17, was stabbed to death in Clowes Park in Salford on January 30.
Detectives have made four arrests - all teenage boys - in connection with his murder but there have been no charges as yet.
Dylan Keelan, 20, was fatally stabbed on Cheetham Hill Road in Dukinfield on February 4.
A 17-year-old boy has been charged with his murder - and investigating detectives have made a series of other arrests in connection with the inquiry.
All three tragedies have been fuelled by further knife attacks and injuries across the city region.
Since launching Operation Sycamore in light of the stabbings, officers say they have arrested 21 people for a range of serious offences.
Arrests have been made for attempted murder, rape, possession of a pointed and bladed article, possession of offensive weapons, public order offences and burglary, GMP said.
Stop and search powers have also been stepped up with 58 being carried out as part of the crackdown.
Nine people searched were found with cannabis and one person was found with a weapon.
Five other weapons - including a machete and a bat - were also seized.
Officers arrested five people on suspicion of drink-driving after stopping 41 vehicles on the roads.
Police chiefs are continuing to urge anyone who is carrying a weapon to surrender it.
The crackdown is set to continue into the coming weeks, with patrols stepped up on the street.
Assistant Chief Constable Chris Sykes of Greater Manchester Police, said: "The impact of three incredibly tragic incidents over recent weeks is still being felt across our communities and GMP is committed to ensuring that the public are kept safe and we remove these lethal weapons from our streets.
"The public want to see police officers on their streets and challenging those who are causing issues, and Operation Sycamore is focused on doing just that.
"This initiative will carry on into the coming weeks and our officers will continue to stop and search individuals when needed, whilst also providing reassurance to members of the public who are concerned about issues in their area.
"I would urge anyone within the community that has information, or suspects someone is carrying a weapon or is involved in criminal behaviour, to report it to us or to contact Crimestoppers.
"I also directly appeal to those carrying weapons to surrender them in our Forever Amnesty bins - no questions asked.
"These are located at 13 police stations across Greater Manchester. These weapons ruin lives and I urge you to do the right thing, before it's too late."
Anyone with information can contact GMP via our LiveChat at gmp.police.uk or 101. In an emergency, always dial 999. Alternatively, contact the independent charity - Crimestoppers, anonymously, on 0800 555 111.