UFC Fight Night 216 predictions: Jared Cannonier or Sean Strickland in 2022’s finale?

	Cannonier vs. Strickland	Ismagulov vs. Tsarukyan	Albazi vs. Costa	Caceres vs. Erosa	Dober vs. Green	Brundage vs. Oleksiejczuk
MMA Junkie readers’ consensus picks 192-116	Cannonier (62%)	Tsarukyan (66%)	Albazi (85%)	Erosa (55%)	Dober (66%)	Oleksiejczuk (71%)
Ken Hathaway @kenshathaway 204-109 2018 Champion	Cannonier	Tsarukyan	Albazi	Erosa	Dober	Oleksiejczuk
Matthew Wells @MrMWells 195-118	Cannonier	Tsarukyan	Albazi	Caceres	Dober	Oleksiejczuk
Abbey Subhan @kammakaze 193-120	Cannonier	Tsarukyan	Albazi	Erosa	Green	Oleksiejczuk
Farah Hannoun @Farah_Hannoun 191-122	Cannonier	Tsarukyan	Albazi	Erosa	Dober	Oleksiejczuk
Mike Bohn @MikeBohn 191-122 2014 Champion	Strickland	Tsarukyan	Albazi	Erosa	Dober	Brundage
Matt Erickson @MMAjunkieMatt 189-124	Cannonier	Ismagulov	Albazi	Caceres	Dober	Oleksiejczuk
Simon Samano @SJSamano 188-125	Strickland	Tsarukyan	Albazi	Erosa	Dober	Oleksiejczuk
Brian Garcia @thegoze 182-131 2017 Champion	Strickland	Tsarukyan	Albazi	Erosa	Green	Brundage
Nolan King @mma_kings 180-133	Cannonier	Tsarukyan	Albazi	Caceres	Green	Oleksiejczuk
George Garcia @MMAjunkieGeorge 172-141	Strickland	Tsarukyan	Albazi	Erosa	Green	Brundage
Danny Segura @dannyseguratv 154-159	N/A	N/A	N/A	N/A	N/A	N/A

The UFC stays in its home base this week, and middleweights are atop the promotion’s final card of the year.

UFC Fight Night 216 takes place Saturday at the UFC Apex in Las Vegas. The card streams on ESPN+.

(Click here to open a PDF of the staff picks grid in a separate window.)

In the main event, recent title challenger Jared Cannonier (15-6 MMA, 8-6 UFC) takes on Sean Strickland (25-4 MMA, 12-4 UFC). The fight nearly is a pick’em at Tipico Sportsbook. Cannonier is the slight favorite at -115; the comeback on Strickland is -105. Our 10 editors, writers, radio hosts and videographers have Cannonier with a narrow 6-4 picks lead.

In the co-feature, Damir Ismagulov (24-1 MMA, 5-0 UFC) meets Arman Tsarukyan (18-3 MMA, 5-2 UFC) at lightweight. Tsarukyan is a -190 betting favorite and a near-unanimous pick at 9-1.

Also on the main card, our lone unanimous pick is Amir Albazi (15-1 MMA, 3-0 UFC) in his flyweight bout against Alessandro Costa (12-2 MMA, 0-0 UFC). Albazi is the biggest favorite on the entire card at -450.

Alex Caceres (19-13 MMA, 14-11 UFC) takes on Julian Erosa (28-9 MMA, 6-5 UFC) in a featherweight fight. Erosa is a mild favorite at -170 and has a 7-3 lead in the picks.

Drew Dober (25-11 MMA, 11-7 UFC) and Bobby Green (29-13-1 MMA, 10-8-1 UFC) clash in a fight between longtime UFC lightweights. Dober is a -150 favorite, but he has just a slim 6-4 lead in the picks.

And to open the main card, Cody Brundage (8-2 MMA, 2-1 UFC) takes on Michal Oleksiejczuk (17-5 MMA, 5-3 UFC) at middleweight. Oleksiejczuk is a big -280 favorite, but three of our pickers are taking Brundage in an upset.

In the MMA Junkie reader consensus picks, Cannonier (62 percent), Tsarukyan (66 percent), Albazi (85 percent), Erosa (55 percent), Dober (66 percent) and Oleksiejczuk (71 percent) are the choices.

Check out all the picks above.

For more on the card, visit MMA Junkie’s event hub for UFC Fight Night 216.