The devastating earthquakes that hit Turkey and Syria early on Monday were the worst the region had experienced in a century - but how can you help?
Over 9,500 people have died and tens of thousands more are injured and missing. Plus there are still daily tremors causing thousands of families' homes to crumble.
Rescuers are clawing through rubble with their bare hands despite the sub-zero temperatures and snow storms the region is also battling.
People have been plunged into homelessness and everyone is scrambling to rescue people trapped under toppled buildings.
In response, charities have set up emergency funds and rescue teams have descended on the region.
To make matters worse, the region where the earthquakes struck is home to significant numbers of Syrian refugees and internally displaced people.
They have already had to flee their homes from nearly 12 years of brutal war.
Some nations have already committed to sending aid, but given the vast scale of destruction, there is still so much more to be done.
Many places are setting up donation points across the UK for material goods, but after an earthquake there is no reliable way to get goods to people. Particularly, in Syria where the regime controls the aid flow.
By donating to the following charities your money will efficiently get what's required for those in need.
Donate to ShelterBox: The Cornwall-based charity provides emergency shelter and disaster relief in Syria and Turkey and will be providing a range of support including tents, shelter kits and cash to affected people.
Donate to CARE: CARE will deliver blankets, food, mattresses, tents, cash assistance and other non-food items to people in Turkey and Syria amid freezing temperatures.
Donate to AKUT: AKUT is the leading search and rescue organisation in Turkey with locations in 32 provinces, supported by 200 permanent members and thousands of volunteers. The organization trains to be prepared for the moment when catastrophe strikes, given the unsuspected nature of natural disasters.
Donate to Turkey Mozaik Foundation: The British-based Foundation supports civil society organisations working on the ground to provide urgent relief in Turkey. Grants will be distributed to carefully selected organisations targeting emergency and longer-term needs.
Donate to Molham: Founded during the Syrian war by a group of students, Molham is on the ground in Syria providing medical equipment such as blood units and intravenous fluid to the wounded people. As well as transporting the injured to hospitals.
Donate to Syria Civil Defence (The White Helmets): Volunteers in Syria have been doing lifesaving and pivotal work, using chainsaws to reach trapped civilians under piles of rubble. They are trained by the organisation but are struggling with the sheer scale of destruction.
Donate to Humanity and Inclusion: The British-run charity supports the most vulnerable people affected, including injured, disabled and older people by distributing mobility aids, and giving emergency rehabilitation services and psychological support.
Donate to SAMS: The Syrian American Medical Society has been working in the hospitals treating thousands of patients, despite some of their clinics being devasted by the quake. You can read an interview with one of their doctors in the Mirror here.