This Morning stars including Holly Willoughby, Alison Hammond and Dermot O'Leary are predicted to be quizzed about Phillip Schofield in an upcoming probe.
It comes after ITV has instructed a barrister to carry out an external review of the facts following Phillip’s statement and departure from This Morning.
ITV chief executive Dame Carolyn McCall is said to have told of the review in a letter seen by PA news agency.
It is believed stars of the show will be asked to give statements to an independent barrister.
Phillip quit the ITV daytime show after 21 years earlier this month following rumours of a feud between himself and his former co-host Holly Willoughby.
Just days later, the presenter admitted to having an "unwise" but not "illegal" affair with a younger ITV employee in an explosive statement.
When announcing the news, Phil, 61, resigned from ITV entirely and was dropped from his talent agency, YMU, for lying about the affair.
Following on from his bombshell statement, a spokesperson for ITV said on Friday the broadcaster was "deeply disappointed" by the "admissions of deceit".
"The relationships we have with those we work with are based on trust," they added.
"Phillip made assurances to us which he now acknowledges were untrue and we feel badly let down."
A later statement from the broadcaster said an internal investigation was launched into allegations of Phillip's affair, but they were "lied" to.
The statement read: "Further to our statement last night, ITV can confirm that when rumours of a relationship between Phillip Schofield and an employee of ITV first began to circulate in early 2020 ITV investigated.
"Both parties were questioned and both categorically and repeatedly denied the rumours as did Phillip's then agency YMU.
"In addition, ITV spoke to a number of people who worked on This Morning and were not provided with, and did not find, any evidence of a relationship beyond hearsay and rumour.
"Phillip’s statement yesterday reveals that he lied to people at ITV, from senior management to fellow presenters, to YMU, to the media and to others over this relationship."
An external review is now set to take place as ITV chief executive Dame Carolyn McCall is said to have told of the review in a letter seen by PA news agency.
The letter was sent to culture secretary Lucy Frazer, DCMS Committee chair Dame Caroline Dinenage and Ofcom’s chief executive Dame Melanie Dawes, in the wake of Schofield’s departure from ITV last week.
It mentions the "significant media coverage concerning Phillip Schofield" and adds that: "As you would expect we take the matter extremely seriously and have reviewed our own records over the weekend."
The letter also mentions that ITV records show "when rumours of a relationship between Phillip Schofield and an employee of ITV first began to circulate in late 2019/early 2020 ITV investigated".
The Mirror has contacted ITV as well as representatives for Holly Willoughby, Alison Hammond and Dermot O'Leary.
