Rangers will be without Mohamed Diomande and John Souttar for the first leg of the Europa League quarter-final against Athletic Bilbao.
Barry Ferguson will have to shuffle his side as the key duo have been ruled out through suspension for the Ibrox contest on Thursday evening.
The pair picked up suspensions in the second leg tie against Fenerbahce in the round of 16 last month.
UEFA rules state players will be suspended for one match in the competition if they receive three cautions.
In the Europa League, the suspension slate is only wiped clean for players after the quarter-final stage meaning just three bookings throughout the league phase and subsequent knockout rounds result in a suspension.
Souttar received his third booking in the competition for pulling down Anderson Talisca. He was previously carded in the first leg against Fenerbahce and at home to Lyon in the second league phase match.
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Diomande previously faced a suspension in the Europa League for three bookings as he missed the league phase contest against Manchester United in January.
Diomande had been cautioned against Malmo, Nice and Tottenham.
UEFA rules state yellow card suspensions will occur after three yellows and then "after any subsequent odd-numbered caution (fifth, seventh, ninth, etc.)".
Diomande was booked against Union Saint-Gilloise and then Fenerbahce to end up suspended against Athletic Bilbao on Thursday.
Rangers Europa League squad
Goalkeepers: Jack Butland, Liam Kelly, Lewis Budinauckas.
Defenders: James Tavernier, Rıdvan Yılmaz, Robin Pröpper, John Souttar, Dujon Sterling, Jefté, Leon Balogun, Clinton Nsiala.
Midfielders: Connor Barron, Mohamed Diomande, Nedim Bajrami, Nicolas Raskin, Ianis Hagi.
Forwards: Cyriel Dessers, Tom Lawrence, Vaclav Cerny, Hamza Igamane, Danilo.
