One person was shot dead on Monday when Sudanese security forces fired live rounds and teargas during protests against military rule that attracted tens of thousands of people, medics said.
Such protests, along with barricades throughout the capital and a general strike last week, have continued since the military took power on Oct. 25, ending a partnership with civilian political parties since the removal of Omar al-Bashir as Sudan's ruler in 2019.
Some 74 civilians have been killed and more than 2,000 injured in crackdowns on the protests, according to the Central Committee of Sudanese Doctors, which is aligned with the protest movement, mainly by gunshots and tear gas canisters.
"Our people are protesting peacefully and using all forms of nonviolent resistance towards a free, democratic and just country, only to be confronted by the military with the worst crimes," the group said.
The protester killed on Tuesday was shot in the chest, the group said, and more protesters were injured in the capital Khartoum and the city of Omdurman.
Police could not immediately be reached for comment.
Military leaders have said the right to peaceful protest is protected and have commissioned investigations into the bloodshed. The violence has deepened the deadlock between pro-democracy groups and the military leadership.
A Reuters witness saw security forces using teargas and stun grenades as protesters stood 1.2 km (0.75 miles) from the presidential palace.
In Omdurman, a Reuters witness saw a heavy security presence and tear gas fired on a main road.
The protests were called by neighbourhood resistance committees, which advocate a stance of "no legitimacy, no negotiation, no partnership" towards the military.
One committee reported the arrest of at least four members. Another said its headquarters were raided.
There were also large protests in the city of Madani, where witnesses said protesters marched towards the house of a protester killed on Friday before heading to the state government building.
Social media users shared images of other protests in the cities of El Fasher, Shendi, and Elobeid.
Last week, the United States condemned the use of force against protesters, saying it would consider additional measures to hold perpetrators of violence accountable.
Military leader Abdelfattah al-Burhan has appointed deputy ministers to a caretaker government which passed this year's budget
On Monday, Abdelghani Alnaeem, former deputy foreign minister under Bashir, confirmed he and more than 100 other diplomats and administrators fired as part of an anti-corruption task force has been re-instated by a judge. "This is a positive step," he said.
(Additional reporting by Moaz Abd-Alaziz; writing by Nafisa Eltahir; Editing by Alex Richardson and Timothy Heritage)