Prime Minister Srettha Thavisin said on Friday he did not agree with allowing recreational use of cannabis, though its medical use would remain under his administration.
"Cannabis policy will be medical cannabis. On recreational use, I do not agree with that," Mr Srettha, who is also finance minister, told reporters.
Thailand's cannabis industry is projected to be worth up to US$1.2 billion (42.9 billion baht) over the next few years, with thousands of businesses springing up since last year's legalisation of the consumption and growing of the drug.
Earlier this week, Mr Srettha unveiled a slew of economic policies aimed at boosting consumption and spending as recovery drags in Southeast Asia's second-biggest economy.
"This is a targeted policy, domestic spending will increase enormously," the former business tycoon said, referring to his signature policy of a 10,000 baht giveaway via digital wallet to all Thais.
On Thursday, the prime minister said the government will use the Krungthai Bank Pao Tang mobile application for its digital wallet project, and the app will be integrated with blockchain technology.