England travel to Murrayfield this weekend as they look to reclaim the Calcutta Cup from Scotland in the opening round of the 2022 Six Nations.
The hosts stunned Eddie Jones's side in their last championship meeting with a first win at Twickenham for 38 years and - according to the England coach - are the "red-hot favourites" to retain the trophy.
Gregor Townsend has named a strong side for the hotly-anticipated clash, with lock Jonny Gray returning to the starting line-up, while England will be led out by new captain Tom Curry for the first time in the absence of injured Owen Farrell.
Here's everything you need to know about Saturday's match:
What time is Scotland v England kick-off?
Scotland v England is due to kick off at 4.45pm on Saturday, February 5, at Murrayfield in Edinburgh.
What TV channel is Scotland v England on? What about live streaming?
Scotland v England is being broadcast live on BBC One with coverage beginning at 4pm.
You will also be able to watch the match via live stream on the BBC iPlayer and BBC Sport website.
What's the Scotland v England team news?
Jonny Gray is set to make his first start for his country in nearly a year, with the Exeter lock a welcome return to Gregor Townsend's side having missed out on the autumn Test matches through injury.
He is joined in the second row by Grant Gilchrist, who will be one appearance away from reaching 50 caps after stepping out against England.
Finn Russell and Ali Price will partner each other at half-back for the fourth consecutive Scotland game, while Duhan Van Der Merwe starts on the wing with Darcy Graham on the other and talismanic captain Stuart Hogg at full-back. Gloucester's Chris Harris and Glasgow's Sam Johnson line up in the centre once again.
In the forwards, Edinburgh duo Jamie Ritchie and Hamish Watson will combine with Matt Fagerson in the back row.
Tom Curry will become England's youngest captain since Will Carling in 1988, with the 23-year-old back-rower appointed after injury ruled Owen Farrell and Courtney Lawes out of contention.
Marcus Smith is set to do battle with Finn Russell as he lines up in a new-look midfield which features Henry Slade at inside centre and Elliot Daly in the No. 13 jersey, with George Ford on the bench.
Joe Marchant has recovered from Covid in time to take his place on the left wing while Max Malins takes the No. 14 jersey, forcing Jack Nowell to settle for a spot among the replacements.
Injuries have led to several changes in the forwards, however, with Maro Itoje joined at lock by Nick Isiekwe, who was only called into the squad last week as cover for Lawes in the hope that the Northampton forward would pass the return-to-play protocols for concussion.
A much-changed back row also sees Curry switched from No. 8 to openside, while Lewis Ludlam takes over at six and Sam Simmonds completes the trio.
Scotland : 15. Stuart Hogg (capt); 14. Darcy Graham, 13. Chris Harris, 12. Sam Johnson, 11. Duhan van der Merwe; 10. Finn Russell, 9. Ali Price; 1. Rory Sutherland, 2. George Turner, 3. Zander Fagerson, 4. Jonny Gray, 5. Grant Gilchrist, 6. Jamie Ritchie, 7. Hamish Watson, 8. Matt Fagerson.
Replacements : 16. Stuart McInally, 17. Pierre Schoeman, 18. WP Nel - Edinburgh Rugby, 19. Sam Skinner, 20. Magnus Bradbury, 21. Ben White, 22 Blair Kinghorn, 23 Sione Tuipulotu.
England: 15. Freddie Steward; 14. Max Malins, 13. Elliot Daly, 12. Henry Slade, 11. Joe Marchant; 10. Marcus Smith, 9. Ben Youngs; 1. Ellis Genge, 2. Luke Cowan-Dickie, 3. Kyle Sinckler, 4. Maro Itoje, 5. Nick Isiekwe, 6. Lewis Ludlam, 7. Tom Curry (capt), 8. Sam Simmonds.
Replacements: 16. Jamie George, 17. Joe Marler, 18. Will Stuart, 19. Charlie Ewels, 20. Alex Dombrandt, 21. Harry Randall, 22. George Ford, 23. Jack Nowell.
Who is the Scotland v England referee?
Referee: Ben O'Keeffe (NZR)
Assistant referees: Nic Berry (RA) and Craig Evans (IRE)
TMO: Ben Whitehouse (WRU)
What have the coaches said?
Scotland head coach Gregor Townsend: “We feel privileged to be involved in the oldest international rugby fixture on Saturday, against our nearest rivals. We are aware of how much winning at Twickenham boosted the spirits of our supporters at the start of last year’s tournament, and we’re looking forward to playing in front of them in person this year.
“We are under no illusions on the tough challenge we have ahead of us against an England side who defeated the World Champions in their last outing.
“The starting 15 we have named has a consistent feel to it which is great for cohesion but we will also benefit from returning players such as Jonny Gray and Rory Sutherland who have been important players for us in recent seasons.
“Ben White has been in very good form for London Irish and has trained well in the last two weeks, so can approach his first involvement at Test level with real confidence.”
On Eddie Jones' claims that Scotland are "red-hot favourites", he said: "Every coach does this little song and dance going into a game trying to convince the media they are underdogs and telling the players their backs are against the wall, 'we're going to this hostile place'. The bookies pick the favourites and I know we're not the favourites with them.
"It's not really something we talk about or worry about. The reason we're being spoken about like that is because our players have driven the standards in training and have gone through experiences - not always pleasant - that have made them better and brought them closer together as a group.
"We have our own expectations, which is to deliver performances that we're capable of. In last year's Six Nations, three games stood out for us where we were close to our best: England, Italy and France. The aim for us is to try to do that in five games."
I think the quality of the northern hemisphere teams has gone up a huge amount in the last few years. I remember when I played and spectated, it was usually only really two teams in the running for the Six Nations. But that's changed. That's been proven in the last few seasons.
"Most teams can beat any other team on their day - and we are one of those teams. We had three wins and two narrow defeats last year and it was a similar story the year before, so we've been very competitive. We've just got to make sure we're continuing to make progress."
England head coach Eddie Jones: "As the first game, this match is hugely important to both sides and we will both want to get off to a winning start.
"We have a good, young team but we understand the task ahead and we’ll be ready to go after it from the first kick.
"Tom Curry will captain the side for this game and has the respect of the team around him, in Owen and Courtney’s absence. He also has the support of the vice captains and other leaders in the team such as Maro Itoje and Ben Youngs.
"We have prepared really well for this game. We’ve had a number of obstacles thrown at us, but we’ve overcome them as a more together group and we’re looking forward to getting started."
He added: "It's the first time I've had the experience of going up there when Scotland have been red-hot favourites. They're expected to win. Every time their players look at the crowd at Murrayfield they'll feel that expectation. They're red hot favourites and they've got to cope with that.
"We can't wait to get up there. And the best thing about it is that we're going to play in Scottish weather.
"This is a special game, the Calcutta Cup. It's been going for 151 years. It means a lot to both countries and it's the first time I've gone there as the underdogs. There'll be 67,000 fans and they'll be thinking about all the fans watching the game on the BBC.
"They have to carry that burden. Every game for us is the same - we're expected to win, so it's no different for us. We're very equipped for it. We're a young but good side. We've had a really good preparation with a few obstacles thrown at us, but we've coped with that really well. The side has come together well - tactically, socially and emotionally."
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