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Scientists achieve record-breaking molecular knot size with practical applications

Scientists break record for the world's tightest knot

Scientists have recently achieved a groundbreaking feat in the field of molecular science: they have created the tightest molecular knot ever recorded. This incredible knot, composed of just tens of atoms, has astonished experts with its complexity and size.

Known as Au6, the molecule self-assembles into a trefoil knot, featuring three crossings. This knot, constructed using a chemical formula called [Au6{1,2-C6H4(OCH2CC)2}3{Ph2P(CH2)4PPh2}3], is the smallest organic trefoil knot ever measured. With a total of 54 atoms, it is 15 atoms smaller than the previous record-holder.

Interestingly, this groundbreaking achievement was accidental. The creation of the trefoil knot occurred when two liquids were mixed together to create other molecular structures called catenanes. However, some of these structures unexpectedly self-assembled into trefoil knots. Professor Richard Puddephatt of the University of Western Ontario, who was involved in the research, commented on this serendipitous discovery.

While this might seem like a technical exercise to an outsider, the practical application of knotting molecules holds great significance. Understanding the process of tying molecules has proven to be highly challenging. However, unraveling this mystery could provide invaluable insights into DNA and other naturally knotted molecules found within the human body.

By developing effective techniques to tie and untie molecules, scientists could potentially unravel the intricate workings of DNA and gain a deeper understanding of how these molecules function. This knowledge could open up new possibilities in various fields, including medicine and biochemistry.

The creation of the tightest molecular knot signifies a remarkable achievement in the realm of scientific inquiry. It not only expands our understanding of molecular structures but also holds the potential to advance our understanding of life itself. As scientists continue to delve into the intricacies of molecular knots, who knows what other fascinating discoveries lie ahead. Exciting times are undoubtedly on the horizon for molecular science.

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