Saturday Night Takeaway and Starstruck have been pulled from the ITV schedules on Saturday, March 19.
Ant and Dec's popular show and the new talent series have been cancelled due to the live Six Nations rugby coverage.
Paul Sinha's new TV show, Sinha's TV Showdown, has also been bumped from the schedule on the same evening to make way for the sport.
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Six Nations Live will run on ITV on Saturday, March 19 from 7.15pm to 10.30pm as England take on France.
It will follow on from Ireland v Scotland which kicks off at 4.45pm, with live coverage from 4pm.
In addition to this, ITV's daytime shows are also set to get a shake-up next week with Loose Women only airing once on Monday, March 14 before it is cancelled.
This is to make way for the Cheltenham Festival which will air from 12.50pm each day.
The major horse racing event will take place from Monday, March 14 to Friday, March 18 with Loose Women expected to return to its usual slot on Monday, March 21.
It's also been reported that the Dancing On Ice final has been postponed for a week so ITV can make way for the FA Cup quarter-final
According to The Sun, DOI viewers will have to wait until Sunday, March 27 to find out who has won this year's series.
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