Several MPs, including the state's new opposition leader David Speirs and his Deputy John Gardner, are set to miss this year's opening of the South Australian parliament after testing positive for COVID-19.
Mr Speirs became infected last week, while Mr Gardner developed symptoms over the weekend and both remain in isolation.
On Monday, former health minister Stephen Wade confirmed he had tested positive while two Labor ministers are believed to have contracted the virus.
They are all expected to be absent when both the House of Assembly and the Legislative Council resume on Tuesday for the first sitting after Labor's resounding election win.
The first sitting also comes amid confusion over the status of former deputy premier Vickie Chapman who recently announced her intention to quit politics despite only getting returned at the March poll.
Ms Chapman had intended to officially resign from the parliament on May 31 and recently wrote to Speaker Dan Cregan outlining her plans.
But Mr Cregan has since advised her that, under the constitution, her resignation appeared to become effective from the date he received her letter late last month.
He said he planned to initiate the process of issuing a writ for a by-election in Ms Chapman's eastern suburbs seat of Bragg on Monday.
That could result in voters going back to the polls soon after the federal election.
Regardless, Ms Chapman was expected to attend parliament's opening after indicating she was still corresponding with Mr Cregan over the issue.
Meanwhile, the government is expected to bring a hefty legislative agenda to the new parliament while the Greens have already detailed a second attempt to have industrial manslaughter laws passed.
Despite having Labor backing, the party's previous bill failed to pass the house before lapsing ahead of the recent election.
Under the Greens' bill an employer could be guilty of an offence, and face a maximum fine of $13 million or up to 20 years imprisonment, if they breached their duty of care and if that breach caused the death of a worker.
"South Australia needs specific laws to protect employees and prevent employers from taking shortcuts that may endanger workers' lives," Greens MP Tammy Franks said.
"This bill seeks to capture a very small minority of employers who cruelly put their workers through unnecessary risk and would only apply in the event that an employee tragically dies.
"As legislators, it is our responsibility to ensure that employers have a genuine incentive to provide a safe workplace.
"We have many carrots in our system, but we do need a few sticks."
