Russian forces are pressing their assault on Ukrainian cities, with new missile strikes and shelling on the edges of the capital Kyiv and the western city of Lviv.
The early morning barrage of missiles on the outskirts of Lviv was the closest strike yet to the centre of the city, which has become a sanctuary city for Ukrainians fleeing the Russian invasion, and for others entering to deliver aid or fight.
Black smoke billowed for hours after the explosions, which hit a facility for repairing military aircraft near the city's international airport about six kilometres from the city centre.
One person was wounded, regional governor Maksym Kozytskyy said.
Multiple blasts hit in quick succession around 6am, shaking nearby buildings, witnesses said.
The missiles were launched from the Black Sea, but the Ukrainian air force's western command said it had shot down two of six missiles in the volley. A bus repair facility was also damaged, Lviv's mayor Andriy Sadoviy said.
Early morning barrages also hit a residential building on the northern edges of Kyiv, killing at least one person, according to emergency services, who said 98 people were evacuated from the building.
Two others were killed when strikes hit residential and administrative buildings in the eastern city of Kramatorsk, according to the regional governor, Pavlo Kyrylenko, and Ukraine's State Service of Special Communications and Information Protection.
Kyiv city authorities said 222 people had been killed in the capital since Russia's invasion of Ukraine began, including 60 civilians and four children.
A further 889 people have been wounded, including 241 civilians, the city administration said in a statement on Friday.
In city after city around Ukraine, hospitals, schools and buildings where people sought safety have been attacked.
Search for survivors continues
Rescue workers searched for survivors in the ruins of a theatre that served as a shelter when it was blown apart by a Russian air strike in the besieged southern city of Mariupol on Wednesday.
Ukrainian human rights ombudswoman Lyudmyla Denisova on Friday said 130 people had been rescued so far from the rubble.
In a televised address, Ms Denisova said rescue work was ongoing at the site, where many people were sheltering underground before the building was hit.
"According to our data there are still more than 1,300 people there who are in these basements, in that bomb shelter," Ms Denisova said, referring to underground shelters below the theatre.
Ukrainian President Volodymyr Zelenskyy later confirmed that rescue work was ongoing to try and rescue "hundreds" feared trapped under the site of the bombed theatre, despite continued Russian attacks on the city.
In an online address on Friday, Mr Zelenskyy said shelling by Russian forces continued to prevent the authorities from establishing effective humanitarian corridors to the encircled port city in southern Ukraine.
Calls for war crimes investigation
As Russian forces pressed their assault on Ukraine, world leaders renewed calls for an investigation of the Kremlin's repeat attacks on civilian targets, including air strikes on schools, hospitals and residential areas.
US Secretary of State Antony Blinken said American officials were evaluating potential war crimes and that if the intentional targeting of civilians by Russia was confirmed, there would be "massive consequences".
Australia and Japan announced separate measures sanctioning Russian individuals and organisations.
The Australian government slapped sanctions on two Russian oligarchs with business interests in the country.
On was Oleg Deripaska, the president of Russian aluminium company Rusal, which has a 20 per cent share in the Queensland Alumina Refinery in Gladstone.
Viktor Vekselberg, who has interests in a company working with Origin Energy to frack the Beetaloo Basin in the Northern Territory, was also added to the official sanctions list, along with 20 Russian businesses.
WHO verifies 43 Russian attacks on hospitals
Despite battleground setbacks and punitive sanctions by the West, Russian President Vladimir Putin has shown little sign of relenting.
His government says it is counting on China to help Russia withstand blows to its economy.
In city after city, hospitals, schools and buildings where people sought safety from the bombardment have been attacked.
Rescue workers continued the search for survivors in the ruins of a theatre that served as a shelter when it was blown apart by a Russian air strike in the besieged city of Mariupol.
In Merefa, near the north-east city of Kharkiv, at least 21 people were killed when Russian artillery destroyed a school and a community centre on Thursday, a local official said.
In the northern city of Chernihiv, dozens of bodies were brought to the morgue in just one day.
World Health Organization (WHO) director-general Tedros Adhanom Ghebreyesus decried the devastating consequences of war on the Ukrainian people.
Dr Ghebreyesus said Ukrainians were struggling to get access to medication, stressing that "the life-saving medicine we need right now is peace".
He told the UN Security Council that the WHO had verified 43 attacks on hospitals and health facilities, with 12 people killed and 34 injured.
The UN human rights office in Geneva said it had recorded 2,149 civilian casualties in Ukraine — 816 killed and 1,333 injured.
Some 3.2 million civilians have fled to neighbouring countries, the UN said.
Bombardment preventing Luhansk evacuations
The governor of Ukraine's eastern Luhansk region said frequent and widespread shelling by Russian forces was preventing the safe evacuation of civilians from towns and villages on the front line.
Luhansk governor Serhiy Gaidai said 59 civilians had been killed in the region since the start of the war, which he said had entirely destroyed some residential areas.
"There is not one community that hasn't been under fire," he said, naming the towns of Severodonetsk, Rubizhne and Popasna as particular hotspots.
Efforts to evacuate civilians have been hampered by the fighting, but local authorities hope a temporary ceasefire can be agreed for Saturday to allow trucks to distribute food, medicine and other aid to people most in need.
Bordering Russia, Luhansk lies in Ukraine's Donbass region that has been partly controlled by Russia-backed separatists since 2014.
ABC/Reuters/AP
