French clubs Paris Saint-Germain and Lille were on Friday drawn against Liverpool and Borussia Dortmund respectively in the last-16 of the Champions League.
Lille reached the knockout phase after finishing the eight-game group stages in seventh place in the 36-team division.
PSG completed the initial section in 15th and were forced to contest two play-off games.
Luis Enrique's men negotiated the obstacle with a 10-0 aggregate destruction of Ligue 1 counterparts Brest.
They will host the Premier League leaders at the Parc des Princes before travelling to Anfield for the return leg a week later.
"With a bit more luck we could have finished with five points more and in the top eight automatic qualifying places for the last-16," said Enrique before the draw.
"But we had to do it the slightly longer way. But no matter, it has prepared us and made us better for what lies ahead.
"We've played teams like Arsenal, Atletico Madrid and Bayern Munich so it's not exactly going to get more difficult. We are ready."
Bid
Lille, who entertain fourth-placed Monaco on Saturday afternoon in Ligue 1, will take on Dortmund in an attempt to the reach the last eight of European club football's most prestigious competition for the first time.
Elsewhere, holders Real Madrid play city rivals Atletico and there is an all-German showdown as Bayern Munich take on Bayer Leverkusen.
The two Dutch teams Feyenoord and PSV Eindhoven take on Inter Milan and Arsenal respectively while Club Brugge pit their wits against Aston Villa and Benfica vie with Barcelona.
The paths to the final in Munich on 31 May were also outlined during the draw at the headquarters in the Swiss city of Nyon of the competition organisers Uefa.
Should PSG eliminate Liverpool, they will take on Club Brugge or Aston Villa in the last eight. Benfica or Barcelona await Lille in the quarter-finals if they can dispose of last season's finalists.
Lyon, the sole French representative in the Europa League, play the Romanian side FCSB. A visit to Real Sociedad or Manchester United follows for the winners of that clash.
