The Duke of Sussex is celebrating the achievements and resilience of seriously ill youngsters and their families during a rare visit to London on Monday.
Harry is attending the WellChild awards ceremony in his role as the charity’s patron, a position he has held for more than 15 years.
On Monday afternoon he arrived at the Royal Lancaster Hotel in Paddington to meet children, teenagers and their parents who will be recognised with awards.
The duke looked relaxed as he began one of only a handful of events he now stages in the UK, following his move to America with his family.
In past years Harry has been joined by wife Meghan but travelled alone this year to London from their home in Montecito in California, where the couple has established a new life for themselves and their children Archie, five, and Lilibet, three.
The visit will raise speculation about whether Harry and his estranged brother the Prince of Wales will see each other, or if the duke will make a trip to Scotland to spend time with his father the King.
It appears unlikely the royal siblings will make contact as the pair reportedly did not talk when they attended a family funeral in August in the UK.
The King is believed to be spending time at his Balmoral home and it is thought he has not seen Harry since the duke rushed to his father’s side after Charles’s cancer diagnosis was announced in February.
The WellChild awards celebrate the inspiring qualities of some of the country’s seriously ill young people and the dedication of those who keep them healthy and happy, including health, social care and education professionals.
Harry regularly attends the annual event hosted by WellChild, the national charity which provides a nationwide network of nurses, home makeover projects and family support programmes.
After attending the reception to meet the category winners and their families he will join guests for the private awards ceremony where he will present the Most Inspirational Child (aged four to six) award and deliver a short speech.
WellChild chief executive Matt James said Harry's involvement with the charity was "huge for us".
He added: "It does two things, it allows us to give our inspiring winners a night they will never forget, a night that will always stay with them.
"But also, it provides us with a platform to tell their stories which is really important for a group of families whose challenges often go unrecognised and misunderstood."