Tottenham’s defeat to Brighton kicked off another packed week of Premier League football in north London on Saturday.
Spurs had been in great form and were looking to further strengthen their grip on fourth place with a fifth successive win, but were well below-par and fell to a 1-0 defeat.
That was a real boost for north London rivals Arsenal, but they could not take advantage and Mikel Arteta’s side fell to a third-straight defeat.
Meanwhile, Roy Hodgson’s Watford were beaten late on by Brentford at Vicarage Road and an immediate return to the Championship now looks almost inevitable.
A Cristiano Ronaldo saw Manchester United edge past Norwich to keep their top-four hopes alive.
A weekend top-flight slate truncated by the FA Cup semi-finals at Wembley continued on Sunday, with West Ham playing out an entertaining draw with relegation-battling Burnley, who made the surprise decision on Friday to sack the Premier League’s longest-serving manager Sean Dyche after 10 years and with only eight games left to play this term.
At the same time, Newcastle fired home a last-second winner at St James’ Park against Leicester.
The action continues with a bumper midweek schedule, as Liverpool moved 4-0 after dismantling Manchester United once again.
That moved Jurgen Klopp’s side two points clear at the top, though Manchester City went back above them after they beat Brighton on Wednesday night.
Elsewhere on Wednesday, Arsenal beat Chelsea in a key all-London showdown at Stamford Bridge.
Premier League table 2021/22
Premier League 2021/22 fixtures, gameweek 33 (all times BST)
Saturday, April 16
1230 | Tottenham 0-1 Brighton
1500 | Manchester United 3-2 Norwich
1500 | Southampton 0-1 Arsenal
1500 | Watford 1-2 Brentford
Sunday, April 17
1415| Newcastle 2-1 Leicester
1415 | West Ham 1-1 Burnley
Tuesday, April 19
2000 | Liverpool 4-0 Manchester United
Wednesday, April 20
1945 | Chelsea 2-4 Arsenal
1945 | Everton 1-1 Leicester
1945 | Newcastle 1-0 Crystal Palace
2000 | Manchester City 3-0 Brighton
Thursday, April 21
1945 | Burnley 2-0 Southampton