The final international break of the season has come and gone meaning it's full steam ahead as the Premier League heads towards its climax.
Manchester City currently lead Liverpool by a point heading into the final run of fixtures as the battle for this season's Premier League crown hots up - and there's plenty to play for elsewhere. Arsenal are in pole position for an all-important top-four finish, but both Tottenham and Manchester United are hot on their heels.
The battle to avoid the dreaded drop will also draw to its conclusion over the coming months as Everton flirt with the prospect of a first top-flight relegation since 1951. With crucial games coming thick and fast, every club will be hoping to enter the run-in with a full squad at their disposal, but the reality is going to be very different.
Here, Mirror Football lists each Premier League club's injury situation - and there are some big names set for spells on the sidelines.
Which team are facing the biggest injury issues? Let us know in the comments below!
Arsenal - 3
Takehiro Tomiyasu (calf), Aaron Ramsdale (groin), Bukayo Saka (illness) - doubtful.
Aston Villa - 2
Marvelous Nakamba (knee) - ruled out.
Kortney Hause (chest) - doubtful.
Brentford - 2
Saman Ghoddas (illness) - ruled out.
Julian Jeanvier (knee) - doubtful.
Brighton - 3
Adam Webster (groin), Adam Lallana (thigh), Tariq Lamptey (illness) - doubtful.
Burnley - 5
Ben Mee (calf), Nathan Collins (suspended), Johann Berg Gudmundsson (calf) - ruled out.
Erik Pieters (knee), Matej Vydra (elbow) - doubtful.
Chelsea - 6
Ben Chilwell (knee) - ruled out.
Callum Hudson-Odoi (calf), Reece James (muscle), Andreas Christensen (muscle), Saul Niguez (illness), Kepa Arrizabalaga (illness) - doubtful.
Crystal Palace - 4
Nathan Ferguson (thigh), James McArthur (knock), Wilfried Zaha (thigh) - ruled out.
Michael Olise (foot) - doubtful.
Everton - 7
Yerry Mina (thigh), Allan (suspended), Tom Davies (thigh), Andros Townsend (knee) - ruled out.
Fabian Delph (thigh), Donny van de Beek (illness), Asmir Begovic (illness) - doubtful.
Leeds - 9
Junior Firpo (knee), Leo Hjelde (knee), Tyler Roberts (thigh), Patrick Bamford (ankle) - ruled out.
Jamie Shackleton (knock), Raphinha (illness), Diego Llorente (back), Mateusz Klich (head), Illan Meslier (groin) - doubtful.
Leicester - 6
Danny Ward (knee), Ryan Bertrand (knee), Wilfred Ndidi (knee) - ruled out.
Jamie Vardy (knee), Marc Albrighton (groin), Wesley Fofana (illness) - doubtful.
Liverpool - 3
Trent Alexander-Arnold (thigh) - ruled out.
James Milner (illness), Naby Keita (knee) - doubtful.
Manchester City - 4
Ruben Dias (thigh), Cole Palmer (ankle), Ederson (illness), John Stones (groin) - doubtful.
Manchester United - 1
Edinson Cavani (calf) - ruled out.
Newcastle - 8
Callum Wilson (calf), Isaac Hayden (knee), Kieran Trippier (ankle), Jamal Lewis (groin) - ruled out.
Federico Fernandez (chest), Jonjo Shelvey (illness), Fabian Schar (groin), Martin Dubravka (illness) - doubtful.
Norwich City - 4
Adam Idah (knee), Andrew Omobamidele (back) - ruled out.
Sam Byram (fitness), Christoph Zimmermann (head) - doubtful.
Southampton - 2
Lyanco (thigh), Alex McCarthy (thigh) - ruled out.
Tottenham - 4
Japhet Tanganga (knee), Ryan Sessegnon (thigh) - ruled out.
Oliver Skipp (groin), Ben Davies (thigh) - doubtful.
Watford - 2
Jeremy Ngakia (thigh), Nicolas Nkoulou (hamstring) - doubtful.
West Ham - 3
Vladimir Coufal (groin), Angelo Ogbonna (knee) - ruled out.
Jarrod Bowen (calf) - doubtful.
Wolves - 5
Ruben Neves (knee), Raul Jimenez (suspended), Ki-Jana Hoever (thigh) - ruled out.
Nelson Semedo (thigh), Pedro Neto (ankle) - doubtful.
