Police arrested two people after a car was spotted driving the wrong way on the A46 through Nottinghamshire.
Officers believed the Ford Focus had been linked to a "knife-related" incident in the Newark area.
Minutes later Nottinghamshire Police received multiple calls saying a car had been seen going the wrong way on the A46 near Farndon.
Read more: Police statement as man stabbed after group enter house 'carrying knives' in Chilwell
Officers claim the vehicle reached up to 100mph as they pursued it.
Police say the Ford crashed into a BMW and spun off the road.
Four occupants in the BMW were injured in the crash but their injuries are not currently believed to be serious.
The road was temporarily closed while the incident was dealt with and both vehicles were recovered. The A46 was reopened by around 1.15am today.
A 24-year-old was arrested on suspicion of dangerous driving, failing to provide a specimen of breath, suspicion of assault occasioning actual bodily harm, possession of a knife in a public place and using threatening behaviour.
A 20-year-old man was detained on suspicion of dangerous driving and driving with excess alcohol.
Detective Chief Inspector Kim Binns, of Nottinghamshire Police, said: “I’d like to commend the good work of the officers and police resources who worked together to try and bring this incident to a safe conclusion. Thanks to their joint efforts two suspects were swiftly located and apprehended.
“It is extremely fortunate that no-one was seriously hurt. As our swift response to this incident shows, the force is committed to keeping people safe and will use all necessary resources to ensure it stays that way.
“The safety of people across Nottinghamshire, including road users, is our priority and I hope our action in this case just goes to show how seriously this kind of behaviour is taken.
“We would now urge anyone who witnessed the incident, or who has dash-cam footage which could assist us with our enquiries, to please get in touch with us.”
Anyone with any information is urged to call Nottinghamshire Police on 101, quoting incident 754 of 25 January 2022, or Crimestoppers anonymously on 0800 555 111.
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