Philippe Clement has named his Rangers side to face Celtic.
The Ibrox boss has made five changes from the draw against Motherwell with Jack Butland and James Tavernier ruled out through injury.
Goalkeeper Butland was admitted to hospital on Hogmanay with a significant internal bleed. He has since been released from care but is unavailable for the derby contest.
Tavernier, meanwhile, picked up an injury in the draw against Motherwell in the final match of 2024.
Tavernier, Kieran Dowell, Oscar Cortes, Danilo and Dessers all drop out of the starting XI from the draw at Fir Park.
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Liam Kelly starts in goal with Ridvan Yilmaz, Robin Propper, Dujon Sterling and Jefte in defence.
Nico Raskin and Mohamed Diomande start in holding midfield with Vaclav Cerny, Ianis Hagi and Nedim Bajrami behind sole striker Hamza Igamane.
RANGERS XI: Kelly, Ridvan, Propper, Sterling, Jefte, Diomande, Raskin, Bajarami, Hagi, Cerny, Igamane.
SUBS: Munn, Cortes, Barron, Dessers, Matondo, Dowell, King, Fraser, Danilo.