Patrick Mahomes Roasted by Fans After Ugly Interception on First Pass vs. Bills

Mahomes leaves the field after warm ups before a game against the Buffalo Bills. | Mark Konezny-Imagn Images

Patrick Mahomes got off to a rough start in the Kansas City Chiefs' Week 11 game in Buffalo against the Bills on Sunday. On his first throw of the day, he tried to quickly get rid of the ball after feeling Buffalo's pressure. Mahomes's pass blooped into the air over Chiefs tight end Noah Gray and right into the arms of Buffalo's Taylor Rapp.

The uncharacteristic mistake right off the bat from the great NFL quarterback led fans to social media to light up Mahomes.

The interception on Kansas City's opening drive definitely wasn't great:

First throw of the game from Patrick Mahomes gets picked 🤯

(via @NFL)pic.twitter.com/Rkdp7YjTre
— Sports Illustrated (@SInow) November 17, 2024

Some fan's reactions were pretty great, though:

Mahomes throws a pick & Romo goes completely silent 😭😭😭😭😭😭
— dyson daniels floater (@killmesIime) November 17, 2024

Mahomes when it comes to first quarter picks pic.twitter.com/vYNxPxHGVc
— BetRivers Sportsbook (@BetRivers) November 17, 2024

lol what a hilarious interception by Mahomes pic.twitter.com/OhWmCqmfQs
— ThatsGoodSports (@BrandonPerna) November 17, 2024

Mahomes throwing that interception pic.twitter.com/Gw2nKQTCM2
— FanDuel (@FanDuel) November 17, 2024

mahomes tossed a pick so and the officials just tossed a flag on the field and then tried to find someway to save him from it, lmao
— one dozen rats at a keyboard (@PanasonicDX4500) November 17, 2024

Mahomes picked off already pic.twitter.com/5NcRqsRAV4
— ᴅ ʀ ᴇ ᴡ (@FeelLikeDrew) November 17, 2024

But, some good news for the Chiefs early in their game in Buffalo:

The Chiefs haven’t lost a game where Patrick Mahomes throws an interception.
— Tucker D. Franklin (@tuckerdfranklin) November 17, 2024

After the interception, the Bills drove down the field before James Cook punched it in for a three-yard score.

Mahomes and the Chiefs couldn't get it going on their second drive either. It was a quick three-and-out with no positive yardage or completions for Mahomes. The next time the Chiefs got the ball, he did find Xavier Worthy for a 10-yard touchdown pass.