Manchester United manager Erik ten Hag has been forced into two major changes at centre-back, with Harry Maguire and Victor Lindelof both starting against Nottingham Forest.
United travel to the City Ground knowing a win would cement their place in the top four, with Newcastle and Tottenham losing to Newcastle and Bournemouth respectively on Saturday. Those results leave all three sides on 56, although Ten Hag's men could rise to 59 come the end of play.
They face a Forest side in the bottom three on goal difference, following a nine-game winless run. But Steve Cooper's side have been far better at home than away, with three draws in their last four including against Manchester City.
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Injuries to Lisandro Martinez and Raphael Varane during Thursday's 2-2 draw with Sevilla have forced Ten Hag into the two changes that will see Harry Maguire and Victor Lindelof pair up at centre-back. Tyrell Malacia is also absent from the squad, with the Dutchman opting to move Diogo Dalot across to left-back, with Aaron Wan-Bissaka on his natural right side.
United will be boosted by the return to domestic action of Casemiro, however, the Brazilian having served his four-game suspension for the red card against Southampton. He starts alongside the ever-present Bruno Fernandes and Marcel Sabitzer
Upfront, Anthony Martial has earned a second consecutive start in the absence of Marcus Rashford, with Antony and Jadon Sancho each holding their places on the right and left wings respectively.
Marc Jurado has also been included in a first-team matchday squad for the first-time in his career, the right-back involved at the City Ground with Luke Shaw yet to recover from his injury.
After the team news came out, many United fans shared the same concern about seeing Lindelof and Maguire back in from the start.
Full United starting line-up: De Gea; Wan-Bissaka, Lindelof, Maguire, Dalot; Casemiro, Fernandes, Sabitzer; Antony, Martial, Sancho
Subs: Butland, Bishop, Jurado, Williams, Eriksen, Fred, Iqbal, Pellistri, Elanga, Weghorst
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