The Dragons have won their first match since a heartbreaking grand final loss in April, kicking off Sunday's action against the Titans.
Later, the Newcastle Knights recorded their first ever victory in the NRLW with a bulldozing win over the Brisbane Broncos.
Look back at all the stats and details from Sunday's games.
Dragons storm past Titans
Jamie Soward has declared Emma Tonegato must play fullback for Australia in the World Cup after starring in St George Illawarra's 26-12 NRLW defeat of Gold Coast.
Dally M medallist in the early-year NRLW competition, Tonegato made a statement to start the second edition of the league in 2022 with a dominant first 20 minutes against the Titans.
Looking dangerous with every touch, the fullback scored the Dragons' opening try when Talei Holmes sent her over in the 12th minute.
She then laid on a superb cut-out pass for debutante winger Andie Robinson, continuing a dream year for the teenager after a hat-trick in under-19s State of Origin..
Tonegato, who represented Australia at the 2013 World Cup, switched to Rugby 7s before returning to rugby league earlier this year.
But she must now firmly be in the conversation to claim the Jillaroos' number one jersey off Tamika Upton.
It is something Dragons coach Soward claims should not even be up for debate, while also admitting his fullback's second half could have been far better on Sunday.
"She will be wearing the number one for Australia," Soward said.
"She's the best number one in the world. And whoever is going to argue that probably doesn't know rugby league.
"She's the best number one in the world. She knows it, I know it, you know it, (Dragons captain) Kezie (Apps) knows it."
Knights beat the Broncos
The Newcastle Knights beat the three-time champion Brisbane Broncos 32-14.
The new-look Newcastle side simply outmuscled perennial heavyweights Brisbane to record their first NRLW win.
The Knights failed to win a game in the postponed 2021 season but went on spending spree in preparation for their second competition, luring stars Millie Boyle, Tamika Upton, Yasmin Clydsdale and Hannah Southwell to the Hunter.
But despite the slew of big names, it was Southwell's younger sister Jesse who led the charge on debut to cement her place as Kirra Dibb's halves partner.
The youngest debutant in NRLW history, the 17-year-old halfback stepped through a hole in the Broncos' defence to open the scoring and finished the night with two line breaks to her name.
Just days after calling out online trolls for body-shaming her, winger Julia Robinson produced a double for the Broncos that had them back in the contest.
But when front-rower Caitlan Johnston crashed over as the final 10 minutes approached, the result was placed beyond doubt for the Knights.