Nine of Vladimir Putin’s military commanders have been wiped out so far in Russia’s invasion of Ukraine.
The commanders are among the 12,000 Russian troops Ukraine now claims it has killed.
It comes as one Kremlin official reportedly described the campaign to subdue the nation as a "clusterf***".
Major General Vitaly Gerasimov has reportedly been killed in fighting outside Ukraine’s second largest city Kharkiv.
The Chief Directorate of Intelligence of Ukraine's defence ministry said in a statement Major Gerasimov was killed on Monday, along with several other officers.
The Kremlin has not commented on the reports.
Gerasimov, first deputy commander of Russia's 41st army, is the second of Putin’s generals to die in the invasion after Major General Andrei Sukhovetsky was taken out by a sniper.
The statement read: “Another loss among the senior command staff of the occupying army.
“During the fighting near Kharkiv, Vitaly Gerasimov, a Russian military leader, major general, chief of staff and first deputy commander of the 41st Army of the Central Military District of Russia, was killed.
"A number of senior Russian army officers were also killed and wounded."
According to The Sun Online reports, Gerasimov had been awarded a medal for "capturing" the disputed province of Crimea in 2014.
He had also received medals after leading troops in Syria and through the second Chechen war.
Several other top commanders have been killed in recent fighting in Ukraine, including Colonel Konstantin Zizevsky of the 247th Air Assault Regiment and Air Assault Brigade Lieutenant Colonel Denis Glebov.
The statement also suggested there were “significant problems” with communication in the Russian army.
Putin previously confirmed the death of Sukhovetsky, the commanding general of the Russian 7th Airborne Division and a deputy commander of the 41st Combined Arms Army, during a speech.
Both Safronov and Glebov were killed when Ukrainian forces recaptured the city of Chuhuiv.
Zizevsky was killed in the south of Ukraine.
Prior to their deaths, Major General Andrei Sukhovetsky was killed by a Ukrainian sniper during the fighting for Hostomel Airfield.
General Magomed Tushaev died when his Chechen special forces column was obliterated near Hostomel, north-east of the city.
Warlord Vladimir Zhonga is also among the dead. Zhonga led the Sparta Battalion, a Neo-Nazi military unit that boasted the backing of the Kremlin.
Ukraine says its forces have killed more than 12,000 Russian troops since the start of the deadly invasion on February 24 while Moscow has so far confirmed about 500 losses.
Neither side has divulged Ukrainian losses.
Today Ukrainian president Volodymyr Zelensky spoke to MPs about the Russian invasion while Boris Johnson continues to encourage Western leaders to punish Russia for the invasion.
Zelensky received a standing ovation at the House of Commons after Speaker Lindsay Hoyle approved a request for a "historic address".
Last night the Ministry of Defence said Russia continued to target civilian evacuation corridors in Ukraine.
The latest intelligence update said: "Russia continues to directly target evacuation corridors, resulting in the death of several civilians whilst trying to evacuate Irpin.
"Due to heavy fighting in the town, it has reportedly been without heat, water or electricity for days."
Attempts to evacuate besieged towns and cities in Ukraine have so far failed owing to continuous Russian shelling at would-be evacuees.
