The 2022 NFL season begins this week. The fun officially begins with a Thursday night game between the Buffalo Bills and Los Angeles Rams.
The betting lines and odds are set for all 16 games this week.
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Who is favored in each game?
Below are the betting odds and lines for all the games of Week 1, according to Tipico Sportsbook.
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Buffalo Bills at Los Angeles Rams
Money line
- Bills (-112)
- Rams (-108)
Spread
- Bills -2.5 (-112)
- Rams +2.5 (-108)
Total
- Over 52.5 (-115)
- Under 52.5 (-105)
New England Patriots at Miami Dolphins
Money line
- Patriots (+140)
- Dolphins (-165)
Spread
- Patriots +3.5 (-125)
- Dolphins -3.5 (+102)
Total
- Over 46.5 (-115)
- Under 46.5 (-105)
Philadelphia Eagles at Detroit Lions
Money line
- Eagles (-190)
- Lions (+160)
Spread
- Eagles -3.5 (-115)
- Lions +3.5 (-105)
Total
- Over 48.5 (-112)
- Under 48.5 (-108)
San Francisco 49ers at Chicago Bears
Money line
- 49ers (-340)
- Bears (+270)
Spread
- 49ers -6.5 (-125)
- Bears +6.5 (+102)
Total
- Over 41.5 (-110)
- Under 41.5 (-110)
Jacksonville Jaguars at Washington Commanders
Money line
- Jaguars (+135)
- Commanders (-160)
Spread
- Jaguars +3.5 (-130)
- Commanders -3.5 (+105)
Total
- Over 43.5 (-115)
- Under 43.5 (-105)
Cleveland Browns at Carolina Panthers
Money line
- Browns (+115)
- Panthers (-135)
Spread
- Browns +2.5 (-105)
- Panthers -2.5 (-115)
Total
- Over 41.5 (-108)
- Under 41.5 (-112)
Indianapolis Colts at Houston Texans
Money line
- Colts (-400)
- Texans (+310)
Spread
- Colts -7.5 (-115)
- Texans +7.5 (-105)
Total
- Over 45.5 (-110)
- Under 45.5 (-110)
Pittsburgh Steelers at Cincinnati Bengals
Money line
- Steelers (+230)
- Bengals (-280)
Spread
- Steelers +6.5 (-112)
- Bengals -6.5 (-108)
Total
- Over 44.5 (-110)
- Under 44.5 (-110)
New Orleans Saints at Atlanta Falcons
Money line
- Saints (-240)
- Falcons (+200)
Spread
- Saints -5.5 (-110)
- Falcons +5.5 (-110)
Total
- Over 42.5 (-112)
- Under 42.5 (-108)
Baltimore Ravens at New York Jets
Money line
- Ravens (-320)
- Jets (+260)
Spread
- Ravens -6.5 (-120)
- Jets +6.5 (+100)
Total
- Over 44.5 (-110)
- Under 44.5 (-110)
Las Vegas Raiders at Los Angeles Chargers
Money line
- Raiders (+145)
- Chargers (-180)
Spread
- Raiders +3.5 (-112)
- Chargers -3.5 (-108)
Total
- Over 52.5 (-108)
- Under 52.5 (-112)
Green Bay Packers at Minnesota Vikings
Money line
- Packers (-125)
- Vikings (+102)
Spread
- Packers -1.5 (-115)
- Vikings +1.5 (-105)
Total
- Over 48.5 (-105)
- Under 48.5 (-115)
Kansas City Chiefs at Arizona Cardinals
Money line
- Chiefs (-205)
- Cardinals (+165)
Spread
- Chiefs -4.5 (-105)
- Cardinals +4.5 (-115)
Total
- Over 53.5 (-115)
- Under 53.5 (-105)
New York Giants at Tennessee Titans
Money line
- Giants (+190)
- Titans (-240)
Spread
- Giants +5.5 (-110)
- Titans -5.5 (-110)
Total
- Over 43.5 (-112)
- Under 43.5 (-108)
Tampa Bay Buccaneers at Dallas Cowboys
Money line
- Buccaneers (-125)
- Cowboys (+102)
Spread
- Buccaneers -1.5 (-112)
- Cowboys +1.5 (-108)
Total
- Over 50.5 (-108)
- Under 50.5 (-112)
Denver Broncos at Seattle Seahawks
Money line
- Broncos (-280)
- Seahawks (+220)
Spread
- Broncos -6.5 (-105)
- Seahawks +6.5 (-115)
Total
- Over 42.5 (-108)
- Under 42.5 (-112)
