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USA Today Sports Media Group
USA Today Sports Media Group
Sport
Jess Root

NFL Week 1 betting picks for winner, spread, total

Week 1 of the 2022 NFL season is underway and will feature 14 Sunday games. That means there are plenty of opportunities for betting action.

The season opener was Thursday and the Buffalo Bills beat the Los Angeles Rams 31-10. I had the Bills winning, covering the spread and the total going under the projection, hitting on all picks.

Buy Cardinals Tickets

As I have done for many seasons, here is where I give you my picks for the money line, spread and total for each of the games the rest of the week.

You can track all my picks on Tallysight each week.

Listen to the latest from Cards Wire’s Jess Root on his podcast, Rise Up, See Red. Subscribe on Apple podcasts or Spotify.

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New Orleans Saints at Atlanta Falcons

Money line: Saints (-230)

Spread: Falcons +4.5 (-108)

Total: Under 42.5 (-112)

Cleveland Browns at Carolina Panthers

Money line: Panthers (-125)

Spread: Panthers -1.5 (-112)

Total: Over 41.5 (-112)

San Francisco 49ers at Chicago Bears

Money line: Bears (+260)

Spread: Bears +6.5 (+100)

Total: Over 40.5 (-110)

Pittsburgh Steelers at Cincinnati Bengals

Money line: Bengals (-280)

Spread: Bengals -6.5 (-108)

Total: Over 44.5 (-105)

Philadelphia Eagles at Detroit Lions

Money line: Lions (+165)

Spread: Lions +3.5 (-103)

Total: Under 48.5 (-108)

Indianapolis Colts at Houston Texans

Money line: Colts (-340)

Spread: Texans +7.5 (-120)

Total: Under 45.5 (-108)

New England Patriots at Miami Dolphins

Money line: Dolphins (-175)

Spread: Dolphins -3.5 (-103)

Total: Under 45.5 (-105)

Baltimore Ravens at New York Jets

Money line: Ravens (-340)

Spread: Jets +7.5 (-120)

Total: Under 44.5 (-110)

Jacksonville Jaguars at Washington Commanders

Money line: Commanders (-135)

Spread: Commanders -2.5 (-117)

Total: Under 43.5 (-103)

Kansas City Chiefs at Arizona Cardinals

Money line: Chiefs (-240)

Spread: Cardinals +5.5 (-105)

Total: Under 53.5 (-109)

Las Vegas Raiders at Los Angeles Chargers

Money line: Chargers (-175)

Spread: Chargers -3.5 (-105)

Total: Over 52.5 (-108)

Green Bay Packers at Minnesota Vikings

Money line: Vikings (-101)

Spread: Vikings +1.5 (-112)

Total: Under 46.5 (-108)

New York Giants at Tennessee Titans

Money line: Titans (-240)

Spread: Titans -5.5 (-110)

Total: Over 43.5 (-112)

Tampa Bay Buccaneers at Dallas Cowboys

Money line: Buccaneers (-135)

Spread: Buccaneers -2.5 (-115)

Total: Under 50.5 (-110)

Denver Broncos at Seattle Seahawks

Money line: Broncos (-270)

Spread: Broncos -6.5 (-105)

Total: Under 44.5 (-110)

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