Week 5 of the 2022 NFL season started out with a dud of a game Thursday night between the Denver Broncos and the Indianapolis Colts. The Colts got the upset win in overtime in a game that stayed Under the projected point total.
There are still no teams on their bye yet so there are 15 games left on the schedule for Sunday and Monday and plenty of options to make some wagers on the games.
Below are my betting picks for the remaining games on the Week 5 schedule. You can track and follow all my picks from each week all season on Tallysight.
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New York Giants vs. Green Bay Packers (London)
Moneyline
- Packers (-375)
Against the spread
- Packers -8 (-110)
Over/Under
- Over 41 (-110)
This will be a blowout win for the Packers, who are playing in London for the first time.
Pittsburgh Steelers at Buffalo Bills
Moneyline
- Bills (-886)
Against the spread
- Bills -14 (-109)
Over/Under
- Over 46.5 (-109)
Kenny Pickett gets his first NFL start but the Bills are devastating and with no T.J. Watt off the edge as a threat to Josh Allen, this could get ugly.
Los Angeles Chargers at Cleveland Browns
Moneyline
- Chargers (-138)
Against the spread
- Chargers -2.5 (-112)
Over/Under
- Over 47.5 (-109)
Myles Garrett returns after his car accident but the Chargers will have too much on offense.
Houston Texans at Jacksonville Jaguars
Moneyline
- Jaguars (-334)
Against the spread
- Texans +7 (-108)
Over/Under
- Over 43.5 (-112)
The Texans manage to keep their games close. Trevor Lawrence bounces back from his atrocious game against the Eagles but it won’t be a blowout.
Chicago Bears at Minnesota Vikings
Moneyline
- Vikings (-324)
Against the spread
- Vikings -7 (-110)
Over/Under
- Under 44 (-111)
The Bears will struggle against the Vikings’ defense.
Detroit Lions at New England Patriots
Moneyline
- Lions (+138)
Against the spread
- Lions +3 (-106)
Over/Under
- Over 45.5 (-110)
The league’s No. 1 offense will still be missing players, but they still put up 45 points last week. Mac Jones might return for the Pats but he will be far from 100% if he does. Otherwise, it will be rookie Bailey Zappe.
Seattle Seahawks at New Orleans Saints
Moneyline
- Saints (-232)
Against the spread
- Seahawks +5.5 (-110)
Over/Under
- Over 46 (-112)
The Seahawks had 48 points last week and Geno Smith threw for more than 300 yards for the second time.
The New Orleans defense will limit them but it will remain a close game.
Miami Dolphins at New York Jets
Moneyline
- Jets (+146)
Against the spread
- Jets +3 (-102)
Over/Under
- Over 45.5 (-110)
Teddy Bridgewater will start for the Dolphins. Zach Wilson led the Jets to a win last week.
Atlanta Falcons at Tampa Bay Buccaneers
Moneyline
- Buccaneers (-396)
Against the spread
- Falcons +8.5 (-110)
Over/Under
- Under 48 (-112)
The Falcons have covered the spread every game this season. They have scored no fewer than 23 points this season. They run the ball very well.
Tennessee Titans at Washington Commanders
Moneyline
- Titans (-136)
Against the spread
- Titans -2.5 (-111)
Over/Under
- Under 42.5 (-110)
Washington’s offense has struggled. The Titans lost WR Treylon Burks to IR.
San Francisco 49ers at Carolina Panthers
Moneyline
- 49ers (-279)
Against the spread
- Panthers +6.5 (-110)
Over/Under
- Over 39 (-113)
The Panthers struggle on offense but will slow the Niners’ running attack to keep it close.
Philadelphia Eagles at Arizona Cardinals
Moneyline
- Eagles (-235)
Against the spread
- Cardinals +5 (-110)
Over/Under
- Over 49 (-112)
The Cardinals will score early to keep this a close game throughout.
Dallas Cowboys at Los Angeles Rams
Moneyline
- Rams (-232)
Against the spread
- Rams -5.5 (-110)
Over/Under
- Over 43 (-110)
Cooper Rush can’t match up with the L.A. defense.
Cincinnati Bengals at Baltimore Ravens
Moneyline
- Bengals (+147)
Against the spread
- Bengals +3 (-105)
Over/Under
- Over 48.5 (-109)
This game will go back and forth but Lamar Jackson will fall short as the Bengals are rounding into form.
Las Vegas Raiders at Kansas City Chiefs
Moneyline
- Chiefs (-336)
Against the spread
- Raiders +7 (-107)
Over/Under
- Under 51 (-110)
This will be a typical, wild AFC West game. The Vegas defense will get to Patrick Mahomes some but it won’t be enough.
