Brendan O'Carroll and Jennifer Gibney are both set to appear in a massive Netflix film coming out in February.
Perry will reprise his role as Madea, who is known for being an elderly and tough woman based on Perry’s mother and aunt, in the flick which will focus on the college graduation of Madea’s great-grandson.
Perry has played Madea in 11 plays and 11 films as well as donning the drag for some TV appearances over the years.
And now we have a trailer for the new film, which will land on the streaming service on February 25.
Speaking on social media after the trailer release, Brendan O'Carroll said: "Ohhh check out the new trailer for A Madea Homecoming, myself & Cathy are both in it, we’re so excited, it’s on #netflix Feb 25th."
Viewers of the preview clip were shocked after seeing the Irish characters pop up in the US made film.
But some have been left less than impressed by the link-up.
One person tweeted: "What the f**k is Mrs Brown doing here?", with a second adding: "How did Mrs Brown from Mrs Browns boys end up in this film! Guessing Tyler Perry has never had to endure an episode."
A third questioned: "Who on earth wanted a Madea and Mrs Brown crossover?"
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However, others were excited to see what short of shenanigans Agnes and Cathy get up to.
One user said: "I am so excited I can’t wait to see what Mrs brown and Cathy are up to."
A second replied: "How exciting!!! Love Madea and Mrs Brown too! Can’t wait to see it!"
While a third said:"Madea vs agnes brown, a match made in a psychiatric ward. I hope Heathrow is included"