A man's horror monkeypox symptom caused his nose to rot away.
The man first visited his GP with a small red spot on his nose - what he believed to be sunburn.
But within a few days, the small mark had turned necrotic - meaning the cells on his nose started to die and rot away.
A picture of the man's nose showed its discolouration and disfigurement, with it scabbed over.
He also developed a number of scabs on his face - caused by the monkeypox virus, reports news.com.au.
The virus can cause a rash, which at first appears similar to chickenpox.
However, the symptoms can morph into firm, puss-filled blisters which then scab over.
More than 35,000 cases of monkeypox had been reported in 92 countries, the World Health Organization confirmed.
Most cases outside of Africa had been in men who have sex with men. The virus is reportedly spreading mostly through sexual activity.
Tests on the male patient in question confirmed he was infected with monkeypox, as well as long-standing syphilis and HIV, of which he was not aware.
Last week, a family dog tested positive for monkeypox, in what may be the first human-to-dog transmission case ever recorded.
Researchers raised the alarm after an Italian greyhound contracted the virus 12 days after its owners started to show their onset symptoms.
Two men attended Pitié-Salpêtrière Hospital, in Paris, France, on June 10, after developing anal ulceration six days after having sex. One man had been experiencing anal ulceration and a rash on his face, ears, and legs, while the other developed a rash just on his legs and back.
In both cases, the men experienced fatigue, headaches, and a fever four days after breaking out in a rash.
They had been co-sleeping with their dog - but said they had been "careful to prevent their dog from contact with other pets or humans from the onset of their own symptoms".
Despite their efforts, their dog tested positive for the monkeypox virus after presenting "mucocutaneous lesions, including abdomen pustules and a thin anal ulceration".
New research, published on The Lancet, a weekly peer-reviewed general medical journal, reads: "On July 23, 2022, monkeypox was declared a Public Health Emergency of International Concern by WHO Director-General Tedros Adhanom Ghebreyesus.
"Human-to-human transmission of monkeypox virus usually occurs through close contact with the lesions, body fluids, and respiratory droplets of infected people or animals.