World number one and defending champion Daniil Medvedev ended the dream US Open run of China's Wu Yibing on Friday to set-up a blockbuster last-16 clash against Nick Kyrgios.
Medvedev eased past world number 174 Wu, who came through qualifying, 6-4, 6-2, 6-2, AFP said.
Wimbledon runner-up Kyrgios made the fourth round by seeing off America's J.J. Wolf 6-4, 6-2, 6-3.
Kyrgios leads the pair's head-to-head record 3-1.
