Manchester United hand Facundo Pellistri a start for tonight’s Europa League clash with Real Betis.
Anthony Martial (hip) and Alejandro Garnacho (ankle) will miss the last-16 second leg in Spain with the Argentine winger confirming he will miss at least the rest of the month following a blow against Southampton on the weekend. Antony has also been ruled out through illness.
With a three-goal cushion, Ten Hag will likely take the chance to rest some of his key players including Marcus Rashford, Bruno Fernandes and Luke Shaw.
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Victor Lindelof has shaken off illness to compete for a spot in the defence.
Casemiro should play given he has been handed a four-game domestic ban, which does not apply to the Europa League.
Marcel Sabitzer is also back in training after a knock but he was named in Austria’s international squad on Wednesday, indicating his imminent return fitness.
Christian Eriksen and Donny van de Beek are long-term absentees for United.
Starting Manchester United XI: De Gea; Wan-Bissaka, Martinez, Maguire, Malacia; Casemiro, Fred; Pellistri, Fernandes, Rashford; Weghorst.