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Erik ten Hag has opted against handing Anthony Martial a first start since his return from injury for Manchester United as Brentford visit Old Trafford.
The Bees head north looking to maintain their European football push against a United side without a Premier League win in three attempts.
A dour performance at Newcastle last time out has left the Red Devils in need of fresh inspiration and Ten Hag questioned his side’s desire after the defeat on Tyneside.
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United were able to call upon Marcus Rashford after he recovered from a toe injury to start while Martial came off the bench having beaten a hip complaint. Wout Weghorst’s struggles in front of goal see him dropped tonight, but it is Rashford who moves up front with Martial still on the bench.
Jadon Sancho comes into the side as a result, while Scott McTominay and Marcel Sabitzer continue in midfield despite failing to impress on the weekend.
Aaron Wan-Bissaka missed the Newcastle game due to illness and returns to the bench, but Donny van de Beek (knee), Alejandro Garnacho (ankle) and Tom Heaton (ankle) remain unavailable.
Christian Eriksen has made his return to first-team training after three months out with an ankle injury, but will not be fit to face his old side.
Casemiro is, once again, suspended for Man United.
Starting XI: De Gea, Dalot, Varane, Martinez, Shaw, McTominay, Sabitzer, Antony, Fernandes, Sancho, Rashford.
Subs: Lindelof, Maguire, Martial, Malacia, Fred, Weghorst, Pellistri, Wan-Bissaka, Butland.