Newcastle United will be looking to keep up their winning streak against the Red Devils following on from big wins against Fulham and Brentford.
The Magpies have a bad record against Man United at Old Trafford with just one win since 1972 at the venue. Last season's fixture resulted in a 4-1 defeat for Steve Bruce and co.
United will head to Manchester spoilt for choice in terms of selection with the majority of the squad fit.
Lee Ryder's prediction
There's a good feeling about this fixture and coupled with Man United's Europa League schedule either side of the last two Premier League games, I think the Magpies will have more energy.
I think Newcastle can win it 2-1 this weekend.
Referee
Craig Pawson (South Yorkshire)
Betting
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Manchester United - Evens
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Draw - 11/4
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Newcastle United - 11/4
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