Manchester United injury woes further mounted on Monday evening with Noussair Mazraoui withdrawing from the Morocco squad.
Argentine winger Alejandro Garnacho earlier in the day was forced to skip international duty with an injury picked up against Aston Villa, and then Kobbie Mainoo's withdrawal from the England squad was confirmed for the same reason.
Having joined Harry Maguire in limping off against Villa on Sunday, Mazraoui appears to have picked up a significant fitness concern which has seen him miss out on Morocco duty during the international break.
It is a quadruple blow for United manager Erik ten Hag, who faces a fight for his job during the pause to the Premier League season having overseen yet another string of disappointing performances and results.
United are next in action on October 19 with the visit of Brentford to Old Trafford, and whomever is sat in the home dugout faces a defensive crisis.
With Maguire and Mazrouai now doubt, they have joined summer signing Leny Yoro, Luke Shaw and Tyrell Malacia in the treatment room.
