Manchester United have lost a number of key players for this afternoon’s trip to Nottingham Forest, including Lisandro Martinez.
The centre-back was forced off with injury late in United’s 2-2 draw in the Europa League with Sevilla and will now miss the rest of the season.
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“I can’t say in this moment, when we have news we will give it to you,” manager Erik ten Hag told reporters on Friday before the severity of the issue was confirmed.
“Let’s do the medical, a full assessment, complete diagnosis, it doesn’t change in this moment. I have an idea but I don’t [want to] cause speculation.”
United are also without Raphael Varane, who came off at half-time against Sevilla with an injury that Ten Hag revealed he has been dealing with for a couple of weeks.
It means Harry Maguire and Victor Lindelof are the centre-back pairing at the City Ground. But no Luke Shaw or Tyrell Malacia means Diogo Dalot lines up at left-back.
Marcus Rashford remains out with a groin injury, with Anthony Martial starting up front again over Wout Weghorst.
Casemiro is back from suspension and features in the Premier League for the first time in more than a month, while Christian Eriksen is on the bench again.
Manchester United XI: De Gea, Wan-Bissaka, Lindelof, Maguire, Dalot, Casemiro, Sabitzer, Fernandes, Antony, Sancho, Martial
Subs: Butland, Jurado, Williams, Eriksen, Fred, Pellistri, Iqbal, Elanga, Weghorst