Kyle Walker and John Stones have been left out of the Manchester City squad who travelled to Sevilla for the club’s first Champions League game of the season.
Walker limped off during Saturday’s draw with Aston Villa while no confirmation was given as to why Stones will miss the trip.
Aymeric Laporte, meanwhile, remains a long-term absentee.
With Pep Guardiola short on defensive numbers, summer signing Manuel Akanji was included in the starting XI, along with Kalvin Phillips.
The latter has struggled with niggles throughout the early stages of his City career, though is in line to make his Champions League bow against Sevilla.
Jack Grealish also travels, with rotation in order as Guardiola juggles a continental campaign with a domestic season he believes will throw up many twists and turns.
Manchester City starting XI (4-3-3): Ederson; Cancelo, Dias, Akanji, Gomez; Rodri, Silva, De Bruyne; Foden, Haaland, Grealish
Injured: Walker, Stones, Laporte