Having knocked out their cross-city rivals in the last-16, Atletico Madrid return to England to take on Manchester City.
The first leg of the Champions League quarter-final will be held at the Etihad Stadium.
Manchester City progressed past Sporting CP to reach the last eight and will have their eye on a place in the semi-finals.
But Diego Simeone’s side know how to frustrate, even with Jose Gimenez missing out after suffering an injury.
Here’s everything you need to know ahead of the first leg:
When and where is it?
The first leg of the quarter-final between Manchester City and Atletico Madrid at the Etihad Stadium is due to kick-off at 8pm BST on Tuesday 5 April.
How can I watch?
Viewers in the United Kingdom can watch Manchester City vs Atletico Madrid on BT Sport 2, with coverage due to begin at 7pm BST. Subscribers can stream the game via the BT Sport app or online player.
Confirmed line-ups
Manchester City XI: Ederson; Stones, Laporte, Ake, Cancelo; Rodrigo, Gundogan; Bernardo, Mahrez, De Bruyne; Sterling
Atletico Madrid XI: Oblak; Vrsaljko, Savić, Felipe, Reinildo, Lodi; M. Llorente, Kondogbia, Koke; Griezmann, João Félix
Odds
Manchester City win: 7/19
Draw: 17/4
Atletico Madrid win: 10/1
Prediction
Atletico Madrid will be tough to break down for Manchester City, particularly away from home, but Pep Guardiola’s side should be able to take a slim first leg advantage to Spain for the second leg. Manchester City 2-1 Atletico Madrid
