Two surprise hopefuls for the Africa Cup of Nations crown will compete for a place in the quarter-finals in Limbe on Wednesday.
Mali topped a group involving Gambia and Tunisia en route to the last-16, two teams which have since gone on to claim their own spot in the quarters.
Mohamed Magassouba’s side are unbeaten in nine games and can harbour genuine ambitions of at least matching the team that finished third in the 2012 and 2013 editions of the competition.
Equiatorial Guinea helped knock holders Algeria out at the group stage after a shock 1-0 win in Douala.
On their only other AFCON appearances, the minnows reached the quarter-finals and semi-finals, in 2012 and 2015 respectively. Can they drum up another run late into the tournament?
Date, kick-off time and venue
Mali vs Equatorial Guinea is scheduled for a 7pm GMT kick-off on Wednesday, January 26, 2022.
Cameroon’s Limbe Stadium will host the match.
Where to watch Mali vs Equatorial Guinea
TV channel: The match will be televised on Sky Sports Premier League.
Live stream: Sky Sports subscribers will be able to watch the match online via the Sky Go app.
Mali vs Equatorial Guinea team news
Moussa Djenepo is again available for Mali after sitting out the Mauritania clash due to a suspension.
Equiatorial Guinea hold doubts over young forward Dorian Hanza after he came off injured in the win over Sierra Leone.
Mali vs Equatorial Guinea prediction
On paper, Mali have the ability to overcome their underdog opponents - but this AFCON has shown that shocks can never be counted out.
Mali to win, 2-1.
Head to head (h2h) history and results
Mali wins: 3
Draws: 0
Equatorial Guinea wins: 0