Uruguay will face Ghana at this year's World Cup in the first meeting between the two countries since Luis Suarez's controversial handball in 2010.
In the 120th minute of the World Cup quarter-final clash between Ghana and Uruguay in 2010, Suarez - then of Ajax - used his hands to stop a certain goal. The score was level at 1-1 and the goal would have all but guaranteed Ghana's place in the semi-finals.
The referee noticed Suarez's offence and sent him off, yet Asamoah Gyan failed to score the resulting penalty. Uruguay then won the shootout in Johannesburg before losing to eventual runners-up Netherlands in the last four. Spain went on to win the tournament.
Ghana would've become the first African team in history to reach the semi-finals of the competition if they'd have won. It's also important to note the tournament was staged in South Africa, the first and only time Africa have hosted a World Cup.
Uruguay and Ghana managed to avoid each other in football since that fateful day, but they will meet again in Qatar on December 2. Suarez, now 35, is expected to be part of his nation's squad for the tournament - his fourth World Cup finals.
Speaking to BBC Sport in 2020, Ghana internationals John Paintsil and Hans Sarpei admitted they "could not forgive" Suarez for his actions in Johannesburg. Paintsil spent six years of his career in England, representing West Ham, Fulham and Leicester.
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"We were cheated," said Paintsil. "To clear the ball from the line with your hand - it's supposed to be a goal... for me, I thought, 'Last man on the line, touch it with his hand, it's supposed to be a goal' - so I was already celebrating that we are through.
"Then I saw it was a penalty and I said, 'What?' I was shouting, 'No, no, take the ball to the centre [circle], take the ball to the centre.'"
Sarpei added: "I can't forgive him because it was not an accident. He knows what he has done. We were crying and you see someone who has cheated us is celebrating. How can I forgive him? Never. Never ever."
Suarez was filmed celebrating after Gyan's penalty was missed, which also annoyed the Ghanaians. "At least be a professional, feel the pain," noted Paintsil. "Just go to your dressing room and celebrate and then nobody will see it."
Suarez - who's won 19 major trophies during this career, including the Champions League and Copa America - admitted he will never visit Africa alone due to the handball. The veteran striker is currently playing for Atletico Madrid after leaving Barcelona in 2020.
"I will never visit Africa on my own, not anytime soon," he said last December. "After my hand save against Ghana. They were through to the semi-finals if I didn't use my hands to save my country. Even if I become a coach, I will coach somewhere else, not there."