Crispin Blunt has become the first Conservative MP to publicly call for Liz Truss to resign.
The MP for Reigate is set to issue his appeal for her resignation as prime minister when he appears on The Andrew Neil Show tonight on Channel 4, where he is to say that the “game is up” for Ms Truss.
Former chancellor George Osborne will also tell the veteran political journalist that Ms Truss will likely be gone “before Christmas”.
Meanwhile, ex-health secretary Matt Hancock is expected to take a more optimistic tack, telling the programme that Ms Truss can survive if she acts now.
Earlier, the former health secretary led calls for the PM to reshuffle her cabinet to add some of the “huge amount of talent on the backbenches”.
The MP, who had to resign as from the health department after being caught violating his own Covid social distancing rules by having an office affair with his aide, added: “I’m not talking about me.”
His comments come days after Ms Truss sacked Kwasi Kwarteng as chancellor to save her reputation following their mini-Budget having trashed the economy when they were both just weeks into their jobs.