Twelve-try Leinster shook off an early Euro hangover to cruise into the URC semi-finals at the RDS.
Leo Cullen's Blues had to pick themselves up quickly after their Champions Cup final disappointment in Marseille last Saturday.
Without skipper Johnny Sexton and with six changes from the team that started that La Rochelle defeat, the reigning champs were still hot favourites to progress to a home last four tie against South African opposition in the shape of the Bulls next Friday night.
Perhaps that's why the 9,346 crowd attendance was well short of capacity but Edinburgh travelled hoping to put doubt in Leinster minds after their European failure, and that's what they managed early on.
It took the hosts over 10 minutes to get going and by that stage they were 7-0 down, having been put on the back foot by stand-in skipper James Ryan's careless penalty concession in the opening seconds.
However once they revved up Leinster proved irresistible, with man of the match Jordan Larmour proving his trajectory is back on an exciting upward curve after a difficult period with injury and non-selection for Ireland.
Early on, Glasgow had two goes at breaching the province's defensive line off lineout ball deep in Leinster territory.
But they stayed patient and grizzled prop Zander Ferguson eventually found the gap to score, with Ross Thompson adding the extras.
Leinster's initial response seemed fuelled by dirty diesel - it was stuttering and disjointed.
But they straightened themselves out on the field after Richie Gray stupidly handed the hosts a personnel advantage.
The experienced Scotland lock fired himself into Jamison Gibson-Park at a ruck and his sin-binning was swiftly punished.
Not surprisingly it was Dan Sheehan who scored Leinster's first try off a lineout maul and, moments after Ross Byrne's successful conversion, Leinster went over for a second.
So impressive in the last URC outing against Munster, Larmour's break had Glasgow in trouble. Gibson-Park couldn't hold his pass but Larmour was on hand to scoop up the loose ball and dive over.
Whatever hope Glasgow still had transformed into frustrated disbelief in the 24th minute, when Joe McCarthy nipped in for his first Leinster try.
Replays showed the ball had dropped out of McCarthy's hand, but the officials deemed it had gone backwards and that he had legitimately dotted it down.
In response, the visitors enjoyed their best spell of the contest but couldn't find a way through and, at the other end, Jimmy O'Brien just failed to find Larmour in the corner.
Moments later, however, the Blues had their fourth try and it was the excellent Sheehan who was again the benefit of a clinical lineout drive before the break.
After that it was a question of how many and Caelan Doris went over for the fifth try in the 43rd minute and sub Michael Ala'alatoa grabbed the sixth.
Byrne's conversion brought up the 40 points with half an hour left before Gibson-Park was pointed the way to the line by Larmour after the winger's break.
And, seconds later, Larmour's alchemy was on hand again as he dipped and dove out of tackles to set up Garry Ringrose for the eighth try.
Glasgow dug deep and found a second try of their own when sub George Horne finished a strong passing move upfield.
However it was but a brief respite and business as usual resumed when Larmour was found for his second try by O'Brien.
Insult to injury was added as far as the visitors were concerned when Ciaran Frawley's interception of Ollie Smith and the conversion by Harry Byrne, who had just replaced his brother Ross, put 50 points between the teams.
Not that Leinster were done, though and another replacement, scrum-half Luke McGrath, went over for their 11th try with 10 minutes to go.
And, just as Lamour was named the man of the match, his back three colleague O'Brien jinked over for his try.
Thankfully for Glasgow, their misery was finally at an end.
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