Keeping Up With The Kardashian fans were shocked to see how much Khloe's appearance has changed from Season 1.
Old clips from the reality show popped up on TikTok, leaving fans stunned at the 37-year-old's changing face.
In the viral clip it showed Khloe talking in interviews from every season of KUWTK.
Over the years her face has slowly changed, with her nose appearing smaller and narrower, cheekbones becoming more prominent and and her lips plumper.
Another said: “Omg this is one hell of a transformation, like I actually find it a bit spooky how much she’s changed over the years… and #15... whoa that was a trip.”
One simply put: “So. Much. Surgery.”
A fan said: "She got lip fillers in season 11 and then after season 15 everything changed."
Another commented: "In season 10 she should have stopped the surgery, she starts to look crazy by season 12 and the way she completely ruined her face with those nose jobs is criminal."
Speaking on the Andy Cohen Show last year, Khloe said she's had a nose job and denies using botox.
Khloe, who has always been very quiet about the procedures she's had done said: "No one's ever asked."
"But after being asked by the show host she said: "Well, for me, everyone says, 'Oh, my gosh, she's had her third face transplant.'
"I've had one nose job - Dr Raj Kanodia," she said, giving the name of the doctor who performed the surgery.
She said that she can't use Botox as she had a bad reaction to it previously.
Eagle-eyed fans once noticed when a completely un-edited photo of Khloe surfaced online.
It was later revealed that the photo was accidentally uploaded by one of the family's assistants.
The image came under heavy scrutiny from fans, prompting Khloe to release a statement about how her mental health has been affected by comments about her appearance.
"In truth, the pressure, constant ridicule and judgement my entire life to be perfect and to meet other's standards of how I should look has been too much to bear," she said.
A cosmetic surgeon explained to the Mirror how he believes he can detect the potential work the reality star has had.
"The bridge of Khloe’s nose appears thinner, and the tip and nostrils appear to be smaller and slightly lifted compared to previous images of her," the surgeon from MYA said.
"A nose changing shape in such a way could only be achieved through surgery rather than contouring. The results of the procedure are very natural and still in-keeping with the natural proportions of her face."
Speaking about further work, the surgeon believes Khloe may have had injections to limit frown lines, as well as cosmetic work done on her breasts.
"I would assume that Khloe may have requested a natural shape with more upper fullness while keeping in proportion with her frame," he explained.
"This can be achieved in many ways depending on the patient's current breast tissue and surgeon recommendation with the choice of implant shape, size and placement of the implants during surgery."