The South Australian Film Corporation will partner with the ABC to produce more content in Adelaide for national and international consumption.
The government will invest $5.2 million over the next three years to develop a pipeline of work and create up to 460 production jobs.
Premier Peter Malinauskas said the film corporation had been telling local stories for more than 50 years, putting South Australians in the spotlight.
"When we have high-quality product and when we have the experience to take Australian culture and deliver it overseas, we are also contributing to our brand as a state and as a nation," he said.
"Australian culture has a lot to offer to other parts of the world, and that's worthy of investment."
ABC managing director David Anderson said the partnership would build a more sustainable production capability in South Australia.
"It's a fight for local content. It's a fight for our local stories being told by us and not having someone else come in and tell them for us," he said.
SA Film Corporation chief executive Kate Croser said the state's screen industry was poised to deliver the highest-quality productions for ABC viewers.
"The recent success of original ABC series from South Australia has paved the way for this consistent stream of production, and demonstrates the capacity of creativity to drive cultural and economic outcomes," she said.