- Kala Pharmaceuticals Inc (NASDAQ:KALA) reported data from a Phase 1b trial of KPI-012, a cell-free secretome therapy for severe ocular diseases driven by impaired healing.
- As previously disclosed, KPI-012 was well tolerated and resulted in significant improvements in various persistent corneal epithelial defect (PCED) etiologies.
- The data will be presented at the 2022 Association for Research in Vision and Ophthalmology.
- KPI-012 resulted in the complete healing of PCED in 6 of 8 participants.
- Improvement in PCED lesion size was observed in those participants who did not heal completely.
- All six healed participants remained healed through the end of the follow-up.
- Related: This Microcap Pharma Stock Almost Doubled Today - Read Why.
- Participants had a mean (SD) improvement in lesion size of -16.23 (12.38) mm2.
- The mean improvement in BCDVA was -0.38 (0.88) logMAR.
- 5 of 8 participants (62.5%) improved their corneal opacity scores from baseline to end of treatment, and 1 had no change in score.
- 100% reported pain reduction by Week 1. There was only one TEAE reported, and it was mild and transient
- The company is on track to submit FDA Investigational New Drug Application (IND) and initiate the Phase 2/3 Trial in 4Q 2022.
- Price Action: KALA shares are up 9.31% at $0.71 during the market session on the last check Monday.
Get all your news in one place.
100’s of premium titles.
One app.
Start reading
One app.
Get all your news in one place.
100’s of premium titles. One news app.
Kala Pharmaceuticals Posts KPI-012 Data In Healing Impaired Ocular Diseases
Sign up to read this article
Read news from 100’s of titles, curated specifically for you.
Already a member?
Sign in here
Top stories on inkl right now
One subscription that gives you access to news from hundreds of sites
Already a member?
Sign in here
Related Stories
Top stories on inkl right now
One subscription that gives you access to news from hundreds of sites
Already a member?
Sign in here
Our Picks