There is unlikely to be a greater contrast in back-to-back away games for Liverpool this season.
After a wet, windy and largely miserable afternoon up in Turf Moor on Sunday - the 1-0 win aside - Jurgen Klopp and his players quickly move on to one of the true cathedrals of football on Wednesday night.
The Reds visit the iconic San Siro for the second time in a little over two months when they are entertained by Inter in the first leg of their Champions League last-16 tie.
It may be Klopp's second trip to Milan since the start of December, but it will be Liverpool's first meeting with the Nerauzzri since a 3-0 aggregate win over the Italians in 2008.
With Luis Diaz registered for the knockout stages following his £50m move from Porto and few injury concerns to worry about, Klopp has a strong set of options to choose from when they take on Simone Inzaghi's side.
So just how will the manager shuffle his options in Milan?
Alisson Becker will continue in goal and it is hard to see the manager adjusting his backline too much for the first leg of a competition Liverpool are looking to win for a seventh time.
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A case could potentially be made for Ibrahima Konate replacing Joel Matip after the latter played 90 minutes against both Leicester and Burnley last week, but the defence is in good shape having conceded just two in their last seven games.
Klopp claimed that Virgil van Dijk was back to his best after the 1-0 win at Burnley and the Dutchman is expected to be named alongside Matip as Trent Alexander-Arnold and Andy Robertson supplement the attack from the full-back areas.
It is, as ever, in midfield where the real debate over team selection comes into play.
Fabinho played an important part in the wins against Leicester and Burnley last week, scoring the only goal in the latter fixture for his fifth in seven matches.
The Brazilian is integral to proceedings in the engine room and will surely start.
Thiago Alcantara could find himself thrust back into the lineup after an encouraging cameo from the bench at Burnley followed his first start of 2022 on Thursday night against Leicester.
Thiago was brought to Anfield for nights like this and an in-form Spain international will be vital to any hopes of success in the tournament he has won twice as a player with Barcelona and Bayern Munich.
Perhaps it also offers a chance for Naby Keita to grasp the nettle once more after starting two of the last three games after his return from the Africa Cup of Nations.
Keita's Champions League campaign ended miserably last season when he was hauled off before half time of a 3-1 defeat to Real Madrid in the Spanish capital and he will be keen to banish those memories with a strong performance in the knockout stages of 2022.
Jordan Henderson's patchy form continued at Burnley as he struggled to impose himself following a return from a back complaint.
It would represent a big call from Klopp to leave out his skipper at the San Siro, but there are others whose recent contributions have been more eye-catching as far as his midfield area goes.
Alex Oxlade-Chamberlain and Curtis Jones are vying for a spot but Klopp has already shown he could spring a surprise by naming Harvey Elliott in a big-game midfield.
Elliott's name on the team sheet raised eyebrows when he began at home to Chelsea back in August, but Klopp has never been afraid of throwing his talented starlets in at the deep end - even if a recent return from long-term injury indicates the 18-year-old will only be given a spot on the bench.
With James Milner also reporting for duty, Klopp has a welcome selection headache in terms of his three-man midfield and the same goes for his attack.
Mohamed Salah, one would expect, will be stationed on the right of the front three, but the German will give serious consideration to the claims of both Sadio Mane and Diaz on the left.
The Reds boss admitted the game at Turf Moor was probably not the desired debut away from Anfield in the Premier League for Diaz, while Mane's inclusion was only because Diogo Jota complained of a dead leg, pre-match.
There is also the option of starting 17-goal Jota on the left to name Roberto Firmino down the middle.
Divock Origi and Takumi Minamino are also cleared for selection but both are expected to find themselves enjoying a watching brief only having missed out on the last two match-day squads.