Ireland have brought back numerous first-string stars for Saturday's Six Nations collision against England at Twickenham, where they hope to end a run of three consecutive defeats.
Skipper Johnny Sexton is one of six changes head coach Andy Farrell has made to his XV for the fourth-round visit to Headquarters, where Ireland will be narrow favourites despite their recent record in London.
Connacht's Bundee Aki is back at inside centre and replaces Robbie Henshaw, who moves to the bench, but there's no place in the squad for Mack Hansen as James Lowe is restored on the left wing.
Ulster's Michael Lowry has also been dropped altogether despite scoring two tries on debut during the 57-6 drubbing of 13-man Italy a fortnight ago, with Hugo Keenan reclaiming the No. 15 jersey.
Loosehead prop Andrew Porter will miss the rest of the tournament after hurting his ankle against the Azzurri, though replacement Cian Healy brings huge experience and will win his 115th cap.
He completes an all-Leinster front row alongside hooker Dan Sheehan and tighthead prop Tadhg Furlong, while James Ryan comes back in at lock alongside Munster's Tadhg Beirne.
The back row of Peter O’Mahony, Josh van der Flier and Caelan Doris remains unchanged, meanwhile, as British and Irish Lion Jack Conan will look to again bring an impact off the bench.
England head coach Eddie Jones was more complimentary than usual in his build-up and attempted to put pressure on the visitors by assuring Ireland are favourites despite having not won at Twickenham since 2018.
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“They are literally, and I say that without any hesitation, the most cohesive side in the world,” said Jones this week of his upcoming opponents.
“The bulk of their team train together for the bulk of the year. So they are very well-coordinated in their attack, they are very structured, they’re very sequenced in set-plays. And they’re tough around the breakdown. So that poses a great challenge for us. But we’re looking forward to the challenge, we’re not intimidated by any team.
“Ireland are favourites for the game, they’ve been in very good form in the autumn, they’re a very settled team, well-coached by Andy Farrell. We’re in a perfect position, aren’t we? They’re flying high, we can’t get our own way or past the barrier according to most journalists."
Just a point separates Ireland in second from England directly below as things stand, and the victors could maintain hope of beating leaders France to the title.
Saturday's match will be Sexton's first since it was announced on Tuesday that he's signed a contract extension through to the 2023 Rugby World Cup, after which he announced he plans to retire.
Even at 36 years of age, the Leinster veteran remains instrumental to the national team's fortunes, and Sexton signalled his intention to "go out on top" when Ireland travel to France in around 18 months.
Les Bleus visit Wales on Friday evening as they look to keep sailing towards the Grand Slam, having already beaten Ireland and with England set to visit Paris on the final weekend.
Ireland team vs. England
(Backs) Hugo Keenan; Andrew Conway, Garry Ringrose, Bundee Aki, James Lowe; Johnny Sexton (capt), Jamison Gibson-Park; (Forwards) Cian Healy, Dan Sheehan, Tadhg Furlong; Tadhg Beirne, James Ryan; Peter O'Mahony, Josh van der Flier, Caelan Doris
Reps: Rob Herring, Dave Kilcoyne, Finlay Bealham, Iain Henderson, Jack Conan, Conor Murray, Joey Carbery, Robbie Henshaw
